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==Overview==
==Overview==
Other imaging studies for meningioma include MR spectroscopy, MR perfusion, and [[angiography]] (DSA).<ref name="R"> Meningioma. Radiopaedia(2015) http://radiopaedia.org/articles/meningioma Accessed on September, 25th 2015</ref> MR spectroscopy study for meningioma demonstrates elevated levels of [[alanine]], [[glutamine]], and [[choline]], as well as a significantly reduced levels of N-acetylaspartate and [[creatine]].<ref name="R"> Meningioma. Radiopaedia(2015) http://radiopaedia.org/articles/meningioma Accessed on September, 25th 2015</ref> MR perfusion study for meningioma demonstrates an elevated value of relative [[cerebral]] blood volume (rCBV).<ref name="pmid21061142">{{cite journal| author=Zimny A, Sasiadek M| title=Contribution of perfusion-weighted magnetic resonance imaging in the differentiation of meningiomas and other extra-axial tumors: case reports and literature review. | journal=J Neurooncol | year= 2011 | volume= 103 | issue= 3 | pages= 777-83 | pmid=21061142 | doi=10.1007/s11060-010-0445-9 | pmc=PMC3116130 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21061142  }} </ref> Angiography of meningioma demonstrates high vascularization of the [[tumor]] due to dual blood supply by both [[pial]] (intracranial) and [[meningeal]] (extracranial) vessels.<ref name="R"> Meningioma. Radiopaedia(2015) http://radiopaedia.org/articles/meningioma Accessed on September, 25th 2015</ref>
Other imaging studies for meningioma include magnetic resonance spectroscopy, magnetic resonance perfusion, and [[angiography]] (DSA).<ref name="R"> Meningioma. Radiopaedia(2015) http://radiopaedia.org/articles/meningioma Accessed on September, 25th 2015</ref> MR spectroscopy study for meningioma demonstrates elevated levels of [[alanine]], [[glutamine]], and [[choline]], as well as a significantly reduced levels of N-acetylaspartate and [[creatine]].<ref name="R"> Meningioma. Radiopaedia(2015) http://radiopaedia.org/articles/meningioma Accessed on September, 25th 2015</ref> MR perfusion study for meningioma demonstrates an elevated value of relative [[cerebral]] blood volume (rCBV).<ref name="pmid21061142">{{cite journal| author=Zimny A, Sasiadek M| title=Contribution of perfusion-weighted magnetic resonance imaging in the differentiation of meningiomas and other extra-axial tumors: case reports and literature review. | journal=J Neurooncol | year= 2011 | volume= 103 | issue= 3 | pages= 777-83 | pmid=21061142 | doi=10.1007/s11060-010-0445-9 | pmc=PMC3116130 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21061142  }} </ref> Angiography of meningioma demonstrates high vascularization of the [[tumor]] due to dual blood supply by both [[pial]] (intracranial) and [[meningeal]] (extracranial) vessels.<ref name="R"> Meningioma. Radiopaedia(2015) http://radiopaedia.org/articles/meningioma Accessed on September, 25th 2015</ref>


==Other Imaging Findings==
==Other Imaging Findings==


'''MR Spectroscopy'''
'''Magnetic resonance spectroscopy'''
* MR spectroscopy imaging may distinguish meningioma from other differential diagnosis. Features include:<ref name="R"> Meningioma. Radiopaedia(2015) http://radiopaedia.org/articles/meningioma Accessed on September, 25th 2015</ref>
* Magnetic resonance spectroscopy (MR) spectroscopy imaging may distinguish meningioma from other differential diagnosis. Features include:<ref name="R"> Meningioma. Radiopaedia(2015) http://radiopaedia.org/articles/meningioma Accessed on September, 25th 2015</ref>
:* Increased [[alanine]] level  
:* Increased [[alanine]] level  
:* Increased [[glutamine]]/[[glutamate]] level     
:* Increased [[glutamine]]/[[glutamate]] level     
Line 16: Line 16:
:* Absent or significantly reduced [[creatine]] (Cr) level
:* Absent or significantly reduced [[creatine]] (Cr) level
          
          
'''MR Perfusion'''
'''Magnetic resonance perfusion'''
* MR perfusion imaging may distinguish meningioma from other differential diagnosis. Features include:<ref name="pmid21061142">{{cite journal| author=Zimny A, Sasiadek M| title=Contribution of perfusion-weighted magnetic resonance imaging in the differentiation of meningiomas and other extra-axial tumors: case reports and literature review. | journal=J Neurooncol | year= 2011 | volume= 103 | issue= 3 | pages= 777-83 | pmid=21061142 | doi=10.1007/s11060-010-0445-9 | pmc=PMC3116130 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21061142  }} </ref>
* Magnetic resonance (MR) perfusion imaging may distinguish meningioma from other differential diagnosis. Features include:<ref name="pmid21061142">{{cite journal| author=Zimny A, Sasiadek M| title=Contribution of perfusion-weighted magnetic resonance imaging in the differentiation of meningiomas and other extra-axial tumors: case reports and literature review. | journal=J Neurooncol | year= 2011 | volume= 103 | issue= 3 | pages= 777-83 | pmid=21061142 | doi=10.1007/s11060-010-0445-9 | pmc=PMC3116130 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21061142  }} </ref>
:* Elevated relative [[cerebral]] blood volume (rCBV) value
:* Elevated relative [[cerebral]] blood volume (rCBV) value
:* Time-intensity curve illustrates a sharp signal drop from baseline with no return to baseline measures
:* Time-intensity curve illustrates a sharp signal drop from baseline with no return to baseline measures

Revision as of 14:45, 28 September 2015

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Haytham Allaham, M.D. [2]

Overview

Other imaging studies for meningioma include magnetic resonance spectroscopy, magnetic resonance perfusion, and angiography (DSA).[1] MR spectroscopy study for meningioma demonstrates elevated levels of alanine, glutamine, and choline, as well as a significantly reduced levels of N-acetylaspartate and creatine.[1] MR perfusion study for meningioma demonstrates an elevated value of relative cerebral blood volume (rCBV).[2] Angiography of meningioma demonstrates high vascularization of the tumor due to dual blood supply by both pial (intracranial) and meningeal (extracranial) vessels.[1]

Other Imaging Findings

Magnetic resonance spectroscopy

  • Magnetic resonance spectroscopy (MR) spectroscopy imaging may distinguish meningioma from other differential diagnosis. Features include:[1]
  • Increased alanine level
  • Increased glutamine/glutamate level
  • Increased choline (Cho) level
  • Absent or significantly reduced N-acetylaspartate (NAA) level
  • Absent or significantly reduced creatine (Cr) level

Magnetic resonance perfusion

  • Magnetic resonance (MR) perfusion imaging may distinguish meningioma from other differential diagnosis. Features include:[2]
  • Elevated relative cerebral blood volume (rCBV) value
  • Time-intensity curve illustrates a sharp signal drop from baseline with no return to baseline measures

Angiography

  • Angiography of meningioma demonstrates:[1]
  • High vascularization of the tumor due to dual blood supply by both pial (intracranial) and meningeal (extracranial) vessels
  • Spoke wheel appearance
  • Dense venous filling

Gallery

References

  1. 1.0 1.1 1.2 1.3 1.4 Meningioma. Radiopaedia(2015) http://radiopaedia.org/articles/meningioma Accessed on September, 25th 2015
  2. 2.0 2.1 Zimny A, Sasiadek M (2011). "Contribution of perfusion-weighted magnetic resonance imaging in the differentiation of meningiomas and other extra-axial tumors: case reports and literature review". J Neurooncol. 103 (3): 777–83. doi:10.1007/s11060-010-0445-9. PMC 3116130. PMID 21061142.