Differentiating tonsillitis from other diseases: Difference between revisions

Jump to navigation Jump to search
Line 51: Line 51:


{| class="wikitable"
{| class="wikitable"
!Variable
!Disease/Variable
!
!Presentation
![[Croup]]
!Causes
![[Epiglottitis]]
!Physical exams findings
![[Pharyngitis]]
!Age commonly affected
![[Tracheitis|Bacterial tracheitis]]
!Imaging finding
![[Tonsilitis]]
!Treatment
![[Retropharyngeal abscess]]
![[Subglottic stenosis]]
|-
|-
| rowspan="4" |Presentation
|[[Peritonsillar abscess]]
|[[Cough]]
|Severe [[sore throat]], [[otalgia]] [[fever]], a "hot potato" or muffled voice, [[drooling]], and [[trismus]]<ref name="pmid18246890" />
|
|[[Streptococcus pyogenes|Aerobic and anaerobic]]
|<small>—</small>
[[Streptococcus pyogenes|bacteria most common is]]
| rowspan="4" |[[Sore throat]], pain on swallowing, [[fever]], [[headache]], [[Abdominal pain|abdominal]] pain, [[nausea]] and [[vomiting]]
| rowspan="4" |Barking [[cough]], [[stridor]],


[[fever]], [[chest pain]],
[[Streptococcus pyogenes|Streptococcus]]  


[[ear pain]], [[difficulty breathing]], [[headache]], [[dizziness]].
[[Streptococcus pyogenes|pyogenes]].<ref name="pmid15573356" /><ref name="pmid18039418" /><ref name="pmid1875138" /><ref name="pmid12092281" />
| rowspan="4" |[[Sore throat]], pain on swallowing, [[fever]], [[headache]], [[cough]]
|[[Contralateral]] deflection of the [[uvula]],
| rowspan="4" |[[Neck pain]], [[stiff neck]], [[torticollis]]  
the [[tonsil]] is displaced [[inferiorly]] and [[medially]], tender [[submandibular]] and [[anterior]] [[cervical lymph nodes|cervical lymph nodes,]] [[Tonsillar abscess|tonsillar]] [[hypertrophy]] with likely peritonsillar [[edema]].
 
|The highest occurrence is in adults between 20 to 40 years of age.<ref name="pmid18246890" />
[[fever]], [[malaise]], [[stridor]], and barking [[cough]]
|On ultrasound peritonsillar abscess appears as focal irregularly marginated hypoechoic area.<ref name="pmid15635144" /><ref name="pmid1642863" /><ref name="pmid26637999" /><ref name="pmid10435129" /><ref name="pmid15635144" /><ref name="pmid1642863" />
| rowspan="4" |Depends on severity. May have respiratory distress at birth, exercise-induced [[dyspnea]],  intermittent [[wheezing]]. Inspiratory [[stridor]]. <ref name="pmid26132943">{{cite journal| author=Nussbaumer-Ochsner Y, Thurnheer R| title=IMAGES IN CLINICAL MEDICINE. Subglottic Stenosis. | journal=N Engl J Med | year= 2015 | volume= 373 | issue= 1 | pages= 73 | pmid=26132943 | doi=10.1056/NEJMicm1404785 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26132943  }}</ref>
|[[Ampicillin-sulbactam|Ampicillin-sulbactam,]]  [[Clindamycin]], [[Vancomycin]] or [[Linezolid]]
|-
|-
|[[Stridor]]
|[[Croup]]
|
|Has [[cough]] and [[stridor]] but no [[drooling]]. Others are [[Hoarseness]], [[Difficulty breathing]], symptoms of the [[common cold]], [[Runny nose]], [[Fever]]
|
|[[Parainfluenza virus]]
|[[Suprasternal notch|Suprasternal]] and [[intercostal]] [[Indrawing|indrawing,]]<ref name="pmid19445760" /> Inspiratory [[stridor]]<ref name="Cherry2008" />, expiratory [[wheezing]],<ref name="Cherry2008" />  [[Sternal]] wall retractions<ref name="pmid194457602" />
|Mainly 6 months and 3 years old
rarely, adolescents and adults<ref name="pmid8769531" />
|[[Steeple sign]] on neck X-ray
|[[Dexamethasone]] and nebulised [[epenephrine|epinephrine]]
|-
|-
|[[Drooling]]
|[[Epiglottitis]]
|<small></small>
|[[Stridor]] and [[drooling]] [[Difficulty breathing|but no cough. Other symptoms include difficulty breathing]], [[Difficulty swallowing|fever, chills, difficulty swallowing]], [[hoarseness]] of [[voice]]
|✔
|[[Hemolysis|H. influenza type b,]]
[[Hemolysis|beta-hemolytic]] [[streptococci]], ''[[Staphylococcus aureus]],''
 
[[fungi]] and [[viruses]].
|[[Cyanosis]], [[Cervical]] [[lymphadenopathy]], [[Inflamed]] [[epiglottis]]
|Used to be mostly found in
pediatric age group between 3 to 5 years,
 
however, recent trend favors adults
 
as most commonly affected individuals<ref name="pmid270310102" />
 
with a mean age of 44.94 years
|[[Thumbprint sign]] on neck x-ray
|[[Airway]] maintenance, [[Parenteral|parenteral]] [[Cefotaxime]] or [[Ceftriaxone]] in combination with [[Vancomycin]]. [[Adjuvant therapy]] includes [[corticosteroids]] and [[racemic]] [[Epinephrine]].<ref name="pmid15983574" /><ref name="pmid12557859" />
|-
|-
| colspan="2" |Others are [[Hoarseness]], [[Difficulty breathing]], symptoms of the [[common cold]], [[Runny nose]], [[Fever]]
|[[Pharyngitis]]
|[[Difficulty breathing|Other symptoms include difficulty breathing]], [[Difficulty swallowing|fever, chills, difficulty swallowing]], [[hoarseness]] of voice
|[[Sore throat]], pain on swallowing, [[fever]], [[headache]], [[abdominal pain]], [[nausea]] and [[vomiting]]
|-
|[[Group A beta-hemolytic streptococci|Group A beta-hemolytic]]
|Causes
[[Group A beta-hemolytic streptococci|streptococcus]].
| colspan="2" |[[Parainfluenza virus]]
|[[Inflamed]] [[pharynx]] with or without [[exudate]]
|[[Hemolysis|H. influenza type b, beta-hemolytic]] [[streptococci]], ''[[Staphylococcus aureus]],'' [[fungi]] and [[viruses]].
|Mostly in children and young adults,
|[[Group A beta-hemolytic streptococci|Group A beta-hemolytic streptococcus]].
with 50% of cases identified
|[[Staphylococcus aureus]]
|Most common cause is viral including [[adenovirus]], [[rhinovirus]], [[influenza]], [[coronavirus]], and [[respiratory syncytial virus]]. Second most common causes are bacterial; ''[[Group A streptococcal infection|Group A streptococcal bacteria]]'',<ref name="pmid3601520">{{cite journal |author=Putto A |title=Febrile exudative tonsillitis: viral or streptococcal? |journal=[[Pediatrics]] |volume=80 |issue=1 |pages=6–12 |year=1987 |pmid=3601520 |doi= |issn=}}</ref> 
|Polymicrobial infection. Mostly; [[Streptococcus pyogenes]], [[Staphylococcus aureus]] and respiratory anaerobes (example; Fusobacteria, [[Prevotella species|Prevotella]], and Veillonella species)<ref name="pmid23520072">{{cite journal| author=Cheng J, Elden L| title=Children with deep space neck infections: our experience with 178 children. | journal=Otolaryngol Head Neck Surg | year= 2013 | volume= 148 | issue= 6 | pages= 1037-42 | pmid=23520072 | doi=10.1177/0194599813482292 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=23520072  }} </ref><ref name="pmid22481424">{{cite journal| author=Abdel-Haq N, Quezada M, Asmar BI| title=Retropharyngeal abscess in children: the rising incidence of methicillin-resistant Staphylococcus aureus. | journal=Pediatr Infect Dis J | year= 2012 | volume= 31 | issue= 7 | pages= 696-9 | pmid=22481424 | doi=10.1097/INF.0b013e318256fff0 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22481424  }} </ref><ref name="pmid18948832">{{cite journal| author=Inman JC, Rowe M, Ghostine M, Fleck T| title=Pediatric neck abscesses: changing organisms and empiric therapies. | journal=Laryngoscope | year= 2008 | volume= 118 | issue= 12 | pages= 2111-4 | pmid=18948832 | doi=10.1097/MLG.0b013e318182a4fb | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18948832  }} </ref><ref name="pmid15573356">{{cite journal| author=Brook I| title=Microbiology and management of peritonsillar, retropharyngeal, and parapharyngeal abscesses. | journal=J Oral Maxillofac Surg | year= 2004 | volume= 62 | issue= 12 | pages= 1545-50 | pmid=15573356 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15573356  }} </ref><ref name="pmid18427007">{{cite journal| author=Wright CT, Stocks RM, Armstrong DL, Arnold SR, Gould HJ| title=Pediatric mediastinitis as a complication of methicillin-resistant Staphylococcus aureus retropharyngeal abscess. | journal=Arch Otolaryngol Head Neck Surg | year= 2008 | volume= 134 | issue= 4 | pages= 408-13 | pmid=18427007 | doi=10.1001/archotol.134.4.408 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18427007  }} </ref><ref name="pmid2235179">{{cite journal| author=Asmar BI| title=Bacteriology of retropharyngeal abscess in children. | journal=Pediatr Infect Dis J | year= 1990 | volume= 9 | issue= 8 | pages= 595-7 | pmid=2235179 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=2235179  }} </ref>
|Congenital, trauma
|-
|Physical exams findings
| colspan="2" |Suprasternal and [[intercostal]] [[Indrawing|indrawing,]]<ref name="pmid19445760">{{cite journal |vauthors=Johnson D |title=Croup |journal=BMJ Clin Evid |volume=2009 |issue= |pages= |year=2009 |pmid=19445760 |pmc=2907784 |doi= |url=}}</ref> Inspiratory [[stridor]]<ref name="Cherry2008">{{cite journal|last1=Cherry|first1=James D.|title=Croup|journal=New England Journal of Medicine|volume=358|issue=4|year=2008|pages=384–391|issn=0028-4793|doi=10.1056/NEJMcp072022}}</ref>, expiratory [[wheezing]],<ref name="Cherry2008">{{cite journal|last1=Cherry|first1=James D.|title=Croup|journal=New England Journal of Medicine|volume=358|issue=4|year=2008|pages=384–391|issn=0028-4793|doi=10.1056/NEJMcp072022}}</ref>  [[Sternal]] wall retractions<ref name="pmid194457602">{{cite journal |vauthors=Johnson D |title=Croup |journal=BMJ Clin Evid |volume=2009 |issue= |pages= |year=2009 |pmid=19445760 |pmc=2907784 |doi= |url=}}</ref>
|[[Cyanosis]], [[Cervical]] [[lymphadenopathy]], Inflammed [[epiglottis]]
|Inflammed [[pharynx]] with or without [[exudate]]
|Subglottic narrowing with purulent secretions in the trachea<ref name="pmid6869336">{{cite journal| author=Liston SL, Gehrz RC, Siegel LG, Tilelli J| title=Bacterial tracheitis. | journal=Am J Dis Child | year= 1983 | volume= 137 | issue= 8 | pages= 764-7 | pmid=6869336 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=6869336  }} </ref><ref name="pmid7271556">{{cite journal| author=Liston SL, Gehrz RC, Jarvis CW| title=Bacterial tracheitis. | journal=Arch Otolaryngol | year= 1981 | volume= 107 | issue= 9 | pages= 561-4 | pmid=7271556 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7271556  }} </ref>
|[[Fever]], especially 100°F or higher.<ref name="Tonsillitis">Tonsillitis. Medline Plus. https://www.nlm.nih.gov/medlineplus/ency/article/001043.htm. Accessed May 2nd, 2016.</ref><ref name="urlTonsillitis - NHS Choices">{{cite web |url=http://www.nhs.uk/Conditions/Tonsillitis/Pages/Introduction.aspx |title=Tonsillitis - NHS Choices |format= |work= |accessdate=}}</ref>[[Erythema]], [[edema]] and [[Exudate]] of the [[tonsils]].<ref name="pmid25587367">{{cite journal |vauthors=Stelter K |title=Tonsillitis and sore throat in children |journal=GMS Curr Top Otorhinolaryngol Head Neck Surg |volume=13 |issue= |pages=Doc07 |year=2014 |pmid=25587367 |pmc=4273168 |doi=10.3205/cto000110 |url=}}</ref> cervical [[lymphadenopathy]], [[Dysphonia]].<ref name="urlTonsillitis - Symptoms - NHS Choices">{{cite web |url=http://www.nhs.uk/Conditions/Tonsillitis/Pages/Symptoms.aspx |title=Tonsillitis - Symptoms - NHS Choices |format= |work= |accessdate=}}</ref>
|Child may be unable to open the mouth widely. May have enlarged


[[cervical]] [[lymph nodes]] and neck mass.
between the ages of 5 to 24 years.<ref name=":0" />
|Signs of respiratory distress,  intermittent [[wheezing]]. Inspiratory [[stridor]]. <ref name="pmid26132943" />
|_
|[[Antimicrobial]] therapy mainly [[penicillin]]-based and [[analgesics]].
|-
|-
|Age commonly affected
|[[Tonsilitis]]
| colspan="2" |Mainly 6 months and 3 years old
|[[Sore throat]], pain on swallowing, [[fever]], [[headache]], and [[cough]]
rarely, adolescents and adults<ref name="pmid8769531">{{cite journal| author=Tong MC, Chu MC, Leighton SE, van Hasselt CA| title=Adult croup. | journal=Chest | year= 1996 | volume= 109 | issue= 6 | pages= 1659-62 | pmid=8769531 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=8769531  }}</ref>
|Most common cause is
|Used to be mostly found in
[[viral]] including [[adenovirus]],


pediatric age group between 3 to 5 years,
[[rhinovirus]], [[influenza]],


however, recent trend favors adults
[[coronavirus]], and


as most commonly affected individuals<ref name="pmid270310102">{{cite journal| author=Lichtor JL, Roche Rodriguez M, Aaronson NL, Spock T, Goodman TR, Baum ED| title=Epiglottitis: It Hasn't Gone Away. | journal=Anesthesiology | year= 2016 | volume= 124 | issue= 6 | pages= 1404-7 | pmid=27031010 | doi=10.1097/ALN.0000000000001125 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27031010  }}</ref>
[[respiratory syncytial virus]].


with a mean age of 44.94 years.
Second most common
|Mostly in children and young adults,


with 50% of cases identified
causes are bacterial;


between the ages of 5 to 24 years.<ref>{{cite book | last = Bennett | first = John | title = Mandell, Douglas, and Bennett's principles and practice of infectious diseases | publisher = Elsevier/Saunders | location = Philadelphia, PA | year = 2015 | isbn = 978-1455748013 }}</ref>
''[[Group A streptococcal infection|Group A streptococcal]]''  
|Mostly during the first six years of life
|Primarily affects children


between 5 and 15 years old.<ref name="Oroface">{{cite book |last1=Sharav |first1=Yair |last2=Benoliel |first2=Rafael |date=2008 |title=Orofacial Pain and Headache |url= |location= |publisher=Elsevier |page= |isbn=0723434123}}</ref>
''[[Group A streptococcal infection|bacteria]]'',<ref name="pmid3601520" />
|Mostly between 2-4 years, but can occur in other age groups.<ref name="pmid12777558">{{cite journal| author=Craig FW, Schunk JE| title=Retropharyngeal abscess in children: clinical presentation, utility of imaging, and current management. | journal=Pediatrics | year= 2003 | volume= 111 | issue= 6 Pt 1 | pages= 1394-8 | pmid=12777558 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12777558  }}</ref><ref name="pmid1876473">{{cite journal| author=Coulthard M, Isaacs D| title=Neonatal retropharyngeal abscess. | journal=Pediatr Infect Dis J | year= 1991 | volume= 10 | issue= 7 | pages= 547-9 | pmid=1876473 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=1876473  }}</ref>
|[[Fever]], especially 100°F or higher.<ref name="Tonsillitis" /><ref name="urlTonsillitis - NHS Choices" />[[Erythema]], [[edema]] and [[exudate]] of the [[tonsils]],<ref name="pmid25587367" /> cervical [[lymphadenopathy]], and  [[Dysphonia]].<ref name="urlTonsillitis - Symptoms - NHS Choices" />
|May be congenital congenital or acquired. Mean age in acquired is 54.1 years<ref name="pmid28007041">{{cite journal| author=Nicolli EA, Carey RM, Farquhar D, Haft S, Alfonso KP, Mirza N| title=Risk factors for adult acquired subglottic stenosis. | journal=J Laryngol Otol | year= 2017 | volume= 131 | issue= 3 | pages= 264-267 | pmid=28007041 | doi=10.1017/S0022215116009798 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28007041  }}</ref>  
|Primarily affects children
between 5 and 15 years old.<ref name="Oroface" />
|Intraoral or transcutaneous USG may show an [[abscess]] making CT scan unnecessary.<ref name="pmid26527518" /><ref name="pmid25946659" /><ref name="pmid25945805" />
|[[Antimicrobial]] therapy mainly [[penicillin]]-based and [[analgesics]] with [[tonsilectomy]] in selected cases.
|-
|-
|Imaging finding
|[[Retropharyngeal abscess]]
| colspan="2" |[[Steeple sign]] on neck X-ray
|[[Neck pain]], [[stiff neck]], [[torticollis]], [[fever]], [[malaise]], [[stridor]], and barking [[cough]]
|[[Thumbprint sign]] on neck x-ray
|Polymicrobial infection.
|<small>—</small>
Mostly; [[Streptococcus pyogenes|Streptococcus]]
|Lateral neck xray shows intraluminal membranes and tracheal wall irregularity.
 
|Intraoral or transcutaneous USG may show an abscess making CT scan unnecessary.<ref name="pmid26527518">{{cite journal| author=Kawabata M, Umakoshi M, Makise T, Miyashita K, Harada M, Nagano H et al.| title=Clinical classification of peritonsillar abscess based on CT and indications for immediate abscess tonsillectomy. | journal=Auris Nasus Larynx | year= 2016 | volume= 43 | issue= 2 | pages= 182-6 | pmid=26527518 | doi=10.1016/j.anl.2015.09.014 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26527518  }} </ref><ref name="pmid25946659">{{cite journal| author=Nogan S, Jandali D, Cipolla M, DeSilva B| title=The use of ultrasound imaging in evaluation of peritonsillar infections. | journal=Laryngoscope | year= 2015 | volume= 125 | issue= 11 | pages= 2604-7 | pmid=25946659 | doi=10.1002/lary.25313 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25946659  }} </ref><ref name="pmid25945805">{{cite journal| author=Fordham MT, Rock AN, Bandarkar A, Preciado D, Levy M, Cohen J et al.| title=Transcervical ultrasonography in the diagnosis of pediatric peritonsillar abscess. | journal=Laryngoscope | year= 2015 | volume= 125 | issue= 12 | pages= 2799-804 | pmid=25945805 | doi=10.1002/lary.25354 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=25945805  }} </ref>
[[Streptococcus pyogenes|pyogenes]], [[Staphylococcus aureus]] and respiratory [[anaerobes]] (example; Fusobacteria, [[Prevotella species|Prevotella]],
|On CT scan, a mass impinging on the posterior pharyngeal wall with rim enhancement is seen<ref name="pmid15667676">{{cite journal| author=Philpott CM, Selvadurai D, Banerjee AR| title=Paediatric retropharyngeal abscess. | journal=J Laryngol Otol | year= 2004 | volume= 118 | issue= 12 | pages= 919-26 | pmid=15667676 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15667676  }}</ref><ref name="pmid12761699">{{cite journal| author=Vural C, Gungor A, Comerci S| title=Accuracy of computerized tomography in deep neck infections in the pediatric population. | journal=Am J Otolaryngol | year= 2003 | volume= 24 | issue= 3 | pages= 143-8 | pmid=12761699 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12761699  }}</ref>
 
|Bronchoscopy reveals subglottic stenosis. Computed tomography may  reveal a concentric stenotic tracheal segment.<ref name="pmid261329432">{{cite journal| author=Nussbaumer-Ochsner Y, Thurnheer R| title=IMAGES IN CLINICAL MEDICINE. Subglottic Stenosis. | journal=N Engl J Med | year= 2015 | volume= 373 | issue= 1 | pages= 73 | pmid=26132943 | doi=10.1056/NEJMicm1404785 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26132943  }}</ref>
and Veillonella species)<ref name="pmid23520072" /><ref name="pmid22481424" /><ref name="pmid18948832" /><ref name="pmid15573356" /><ref name="pmid18427007" /><ref name="pmid2235179" />
|-
|Child may be unable to open the mouth widely. May have enlarged [[cervical]] [[lymph nodes]] and neck mass.
|Treatment
|Mostly between 2-4 years, but can occur in other age groups.<ref name="pmid12777558" /><ref name="pmid1876473" />
| colspan="2" |[[Dexamethasone]] and nebulised [[epenephrine|epinephrine]]
|On CT scan, a mass impinging on the posterior [[pharyngeal]] wall with rim enhancement is seen<ref name="pmid15667676" /><ref name="pmid12761699" />
|Airway maintenance, p[[Parenteral|arenteral]] [[Cefotaxime]] or [[Ceftriaxone]] in combination with [[Vancomycin]]. Adjuvant therapy includes [[corticosteroids]] and racemic [[Epinephrine]].<ref name="pmid15983574">{{cite journal| author=Nickas BJ| title=A 60-year-old man with stridor, drooling, and "tripoding" following a nasal polypectomy. | journal=J Emerg Nurs | year= 2005 | volume= 31 | issue= 3 | pages= 234-5; quiz 321 | pmid=15983574 | doi=10.1016/j.jen.2004.10.015 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15983574  }}</ref><ref name="pmid12557859">{{cite journal| author=Wick F, Ballmer PE, Haller A| title=Acute epiglottis in adults. | journal=Swiss Med Wkly | year= 2002 | volume= 132 | issue= 37-38 | pages= 541-7 | pmid=12557859 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=12557859  }}</ref>
|Immediate surgical drainage and antimicrobial therapy. emperic therapy involves; [[ampicillin]]-[[sulbactam]] or [[clindamycin]].
|[[Antimicrobial]] therapy mainly [[penicillin]]-based and [[analgesics]].
|Airway maintenance and antibiotics
|[[Antimicrobial]] therapy mainly [[penicillin]]-based and [[analgesics]] with [[tonsilectomy]] in selected cases.
|Immediate surgical drainage and antimicrobial therapy. emperic therapy involves; ampicillin-sulbactam or clindamycin.
|Endoscopic balloon dilation  for patients with low-grade subglottic stenosis,<ref name="pmid27095722">{{cite journal| author=Cui PC, Luo JS, Zhao DQ, Guo ZH, Ma RN| title=[Management of subglottic stenosis in children with endoscopic balloon dilation]. | journal=Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | year= 2016 | volume= 51 | issue= 4 | pages= 286-8 | pmid=27095722 | doi=10.3760/cma.j.issn.1673-0860.2016.04.009 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=27095722  }}</ref> glucocorticoid injections, and resection.<ref name="pmid261329433">{{cite journal| author=Nussbaumer-Ochsner Y, Thurnheer R| title=IMAGES IN CLINICAL MEDICINE. Subglottic Stenosis. | journal=N Engl J Med | year= 2015 | volume= 373 | issue= 1 | pages= 73 | pmid=26132943 | doi=10.1056/NEJMicm1404785 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26132943  }}</ref>
|}
|}



Revision as of 15:41, 21 March 2017

Tonsillitis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Tonsillitis from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

X Ray

USG

CT Scan

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Differentiating tonsillitis from other diseases On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Differentiating tonsillitis from other diseases

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Differentiating tonsillitis from other diseases

CDC on Differentiating tonsillitis from other diseases

Differentiating tonsillitis from other diseases in the news

Blogs on Differentiating tonsillitis from other diseases

Directions to Hospitals Treating Tonsillitis

Risk calculators and risk factors for Differentiating tonsillitis from other diseases

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Luke Rusowicz-Orazem, B.S.

Overview

Tonsillitis must be differentiated from other diseases that present with edema and erythema of the tonsils and nasopharynx, lymphadenopathy, fever, dysphonia, and dysphagia.

Differentiating Tonsillitis from other Diseases

Tonsillitis must be differentiated from other diseases that present with edema and erythema of the tonsils and nasopharynx, lymphadenopathy, fever, dysphonia, and dysphagia.

Disease Findings
Mononucleosis
Retropharyngeal abscess
Epstein Barr virus
Herpes simplex virus pharyngitis
Epiglottitis
Peritonsillar abscess
Diphtheria
HIV


The table below outlines the differences between tonsillitis and other respiratory tract infections.

Disease/Variable Presentation Causes Physical exams findings Age commonly affected Imaging finding Treatment
Peritonsillar abscess Severe sore throat, otalgia fever, a "hot potato" or muffled voice, drooling, and trismus[1] Aerobic and anaerobic

bacteria most common is

Streptococcus

pyogenes.[2][3][4][5]

Contralateral deflection of the uvula,

the tonsil is displaced inferiorly and medially, tender submandibular and anterior cervical lymph nodes, tonsillar hypertrophy with likely peritonsillar edema.

The highest occurrence is in adults between 20 to 40 years of age.[1] On ultrasound peritonsillar abscess appears as focal irregularly marginated hypoechoic area.[6][7][8][9][6][7] Ampicillin-sulbactam, Clindamycin, Vancomycin or Linezolid
Croup Has cough and stridor but no drooling. Others are Hoarseness, Difficulty breathing, symptoms of the common cold, Runny nose, Fever Parainfluenza virus Suprasternal and intercostal indrawing,[10] Inspiratory stridor[11], expiratory wheezing,[11] Sternal wall retractions[12] Mainly 6 months and 3 years old

rarely, adolescents and adults[13]

Steeple sign on neck X-ray Dexamethasone and nebulised epinephrine
Epiglottitis Stridor and drooling but no cough. Other symptoms include difficulty breathing, fever, chills, difficulty swallowing, hoarseness of voice H. influenza type b,

beta-hemolytic streptococci, Staphylococcus aureus,

fungi and viruses.

Cyanosis, Cervical lymphadenopathy, Inflamed epiglottis Used to be mostly found in

pediatric age group between 3 to 5 years,

however, recent trend favors adults

as most commonly affected individuals[14]

with a mean age of 44.94 years

Thumbprint sign on neck x-ray Airway maintenance, parenteral Cefotaxime or Ceftriaxone in combination with Vancomycin. Adjuvant therapy includes corticosteroids and racemic Epinephrine.[15][16]
Pharyngitis Sore throat, pain on swallowing, fever, headache, abdominal pain, nausea and vomiting Group A beta-hemolytic

streptococcus.

Inflamed pharynx with or without exudate Mostly in children and young adults,

with 50% of cases identified

between the ages of 5 to 24 years.[17]

_ Antimicrobial therapy mainly penicillin-based and analgesics.
Tonsilitis Sore throat, pain on swallowing, fever, headache, and cough Most common cause is

viral including adenovirus,

rhinovirus, influenza,

coronavirus, and

respiratory syncytial virus.

Second most common

causes are bacterial;

Group A streptococcal

bacteria,[18]

Fever, especially 100°F or higher.[19][20]Erythema, edema and exudate of the tonsils,[21] cervical lymphadenopathy, and Dysphonia.[22] Primarily affects children

between 5 and 15 years old.[23]

Intraoral or transcutaneous USG may show an abscess making CT scan unnecessary.[24][25][26] Antimicrobial therapy mainly penicillin-based and analgesics with tonsilectomy in selected cases.
Retropharyngeal abscess Neck pain, stiff neck, torticollis, fever, malaise, stridor, and barking cough Polymicrobial infection.

Mostly; Streptococcus

pyogenes, Staphylococcus aureus and respiratory anaerobes (example; Fusobacteria, Prevotella,

and Veillonella species)[27][28][29][2][30][31]

Child may be unable to open the mouth widely. May have enlarged cervical lymph nodes and neck mass. Mostly between 2-4 years, but can occur in other age groups.[32][33] On CT scan, a mass impinging on the posterior pharyngeal wall with rim enhancement is seen[34][35] Immediate surgical drainage and antimicrobial therapy. emperic therapy involves; ampicillin-sulbactam or clindamycin.

References

Template:WH Template:WS