Hereditary nonpolyposis colorectal cancer laboratory findings: Difference between revisions
(Created page with "{{Hereditary nonpolyposis colorectal cancer}} {{CMG}}{{AE}}{{MV}}{{Akram}} ==Overview== Laboratory findings consistent with the diagnosis of hereditary nonpolyposis colorecta...") |
No edit summary |
||
Line 3: | Line 3: | ||
==Overview== | ==Overview== | ||
Laboratory findings consistent with the diagnosis of hereditary nonpolyposis colorectal cancer | [[Medical laboratory|Laboratory]] findings consistent with the [[diagnosis]] of hereditary nonpolyposis colorectal cancer may include positive [[germline]] [[Test|testing]] for hereditary nonpolyposis colorectal cancer [[Gene|genes]] ([[MLH1]], [[MSH2]], [[MSH6]], and [[PMS2]]), positive EPCAM [[gene]] [[Test|testing]], and elevated [[serum]] concentration of [[CEA]] and [[CA-125]]. | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
Laboratory findings consistent with the diagnosis of hereditary nonpolyposis colorectal cancer | [[Medical laboratory|Laboratory]] findings consistent with the [[diagnosis]] of hereditary nonpolyposis colorectal cancer may include:<ref name="pmid24827900">{{cite journal |vauthors=Lynch HT, Drescher K, Knezetic J, Lanspa S |title=Genetics, biomarkers, hereditary cancer syndrome diagnosis, heterogeneity and treatment: a review |journal=Curr Treat Options Oncol |volume=15 |issue=3 |pages=429–42 |year=2014 |pmid=24827900 |doi=10.1007/s11864-014-0293-5 |url=}}</ref> | ||
:*Positive EPCAM gene | :*Positive EPCAM [[gene]] | ||
:*Positive germline testing (MMR) for hereditary nonpolyposis colorectal cancer genes ([[MLH1]], [[MSH2]], [[MSH6]] and [[PMS2|PMS-2]]) | :*Positive [[germline]] [[Test|testing]] (MMR) for hereditary nonpolyposis colorectal cancer [[Gene|genes]] ([[MLH1]], [[MSH2]], [[MSH6]] and [[PMS2|PMS-2]]) | ||
:*Elevated serum concentration of [[CEA]] | :*Elevated [[serum]] concentration of [[CEA]] | ||
:*Elevated serum concentration of CA-125 | :*Elevated [[serum]] concentration of [[CA-125]] | ||
==References== | ==References== |
Latest revision as of 21:23, 29 April 2019
Hereditary Nonpolyposis Colorectal Cancer Microchapters |
Differentiating Hereditary Nonpolyposis Colorectal Cancer from other Diseases |
---|
Diagnosis |
Treatment |
Case Studies |
Hereditary nonpolyposis colorectal cancer laboratory findings On the Web |
American Roentgen Ray Society Images of Hereditary nonpolyposis colorectal cancer laboratory findings |
FDA on Hereditary nonpolyposis colorectal cancer laboratory findings |
CDC on Hereditary nonpolyposis colorectal cancer laboratory findings |
Hereditary nonpolyposis colorectal cancer laboratory findings in the news |
Blogs on Hereditary nonpolyposis colorectal cancer laboratory findings |
Directions to Hospitals Treating Hereditary nonpolyposis colorectal cancer |
Risk calculators and risk factors for Hereditary nonpolyposis colorectal cancer laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]Ali Akram, M.B.B.S.[3]
Overview
Laboratory findings consistent with the diagnosis of hereditary nonpolyposis colorectal cancer may include positive germline testing for hereditary nonpolyposis colorectal cancer genes (MLH1, MSH2, MSH6, and PMS2), positive EPCAM gene testing, and elevated serum concentration of CEA and CA-125.
Laboratory Findings
Laboratory findings consistent with the diagnosis of hereditary nonpolyposis colorectal cancer may include:[1]
References
- ↑ Lynch HT, Drescher K, Knezetic J, Lanspa S (2014). "Genetics, biomarkers, hereditary cancer syndrome diagnosis, heterogeneity and treatment: a review". Curr Treat Options Oncol. 15 (3): 429–42. doi:10.1007/s11864-014-0293-5. PMID 24827900.