Focal segmental glomerulosclerosis causes: Difference between revisions

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{{Focal segmental glomerulosclerosis}}
{{Focal segmental glomerulosclerosis}}
{{CMG}}; '''Associate Editor-In-Chief:’’’ {{CZ}}
{{CMG}} {{AE}} {{MKK}}
==Overview==


==Overview==


==Causes==
===Common Causes===
The cause of focal segmental glomerulosclerosis is usually unknown.
[Disease name] may be caused by:
*[Cause1]
*[Cause2]
*[Cause3
 
 
*[Disease name] is caused by an infection with [pathogen name].
*[Pathogen name] is caused by [pathogen name].
 
===Less Common Causes===
Less common causes of [[disease name]] include:
*[Cause1]
*[Cause2]
*[Cause3]
 
===Genetic Causes===
*Mutations in [[alpha actinin 4]]
*Mutations in NPHS1 ([[nephrin]])
*Mutations in NPHS2 ([[podocin]])
*Mutations in WT-1
*Mutations in [[TRPC6]]
*Mutations in [[SCARB2]] (LIMP2)
*Mutations in INF2 (formin)
*Mutations in CD2-associated protein
*[[Mitochondrial cytopathies]]
 
====Virus Associated====
*[[HIV]]
*[[Parvovirus B19]]
*[[CMV]]
 
====Medication====
*[[Heroin]]
*[[Interferon alpha]]
*[[Lithium]]
*[[Pamidronate]]/aledronate
*[[Anabolic steroids]]
 
=


The condition affects both children and adults. Men and boys are affected slightly more often than women and girls, and it also occurs more often in African Americans. Focal segmental glomerulosclerosis causes about 20 - 25% of all cases of [[nephrotic syndrome]].


Known causes include:
*[[Diabetes mellitus]]
*[[Hypertension]]
*[[Obesity]]
*[[Cyanotic congenital heart disease]]
*[[Sickle cell anemia]]


* [[Heroin]] use
====Malignancy====
* [[HIV]]
*[[Lymphoma]]
* Inherited genetic problems
* [[Obesity]]
* [[Reflux nephropathy]] (a condition in which urine flows backward from the bladder to the kidney)
* [[Sickle cell disease]]


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}


[[Category:Disease]]
[[Category:Kidney diseases]]
[[Category: Channelopathy]]


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{{WH}}
{{WS}}
{{WS}}

Latest revision as of 17:04, 1 June 2018

Focal segmental glomerulosclerosis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Focal segmental glomerulosclerosis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X-Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

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Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

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Risk calculators and risk factors for Focal segmental glomerulosclerosis causes

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]

Overview

Common Causes

[Disease name] may be caused by:

  • [Cause1]
  • [Cause2]
  • [Cause3


  • [Disease name] is caused by an infection with [pathogen name].
  • [Pathogen name] is caused by [pathogen name].

Less Common Causes

Less common causes of disease name include:

  • [Cause1]
  • [Cause2]
  • [Cause3]

Genetic Causes

Virus Associated

Medication

=


Malignancy

References


Template:WH Template:WS