Diabetes mellitus type 2 surgery: Difference between revisions
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{{CMG}};{{AE}}{{MehdiP}} | {{CMG}};{{AE}}{{MehdiP}} | ||
==Overview== | ==Overview== | ||
Pancreas and islet cell transplantation is considered in patients with chronic diabetes who have frequent metabolic complications and are intolerant to exogenous insulin or have failed to insulin therapy. | Pancreas and islet cell transplantation is considered in patients with chronic diabetes who have frequent [[metabolic]] complications and are intolerant to exogenous [[insulin]] or have failed to insulin therapy. | ||
==Surgery== | ==Surgery== | ||
There is no indication for surgery in type 2 diabetes mellitus unless, there is an indication for pancreas and islet cell transplantation. Pancreas and islet transplantation have been shown to normalize glucose levels but require lifelong immunosuppression to prevent graft rejection and recurrence of autoimmune islet destruction. although, islet cell transplantation remains investigational. Pancreas transplantation is considered for patients with chronic diabetes and multiple complications.<br> | There is no indication for surgery in type 2 diabetes mellitus unless, there is an indication for pancreas and islet cell transplantation. Pancreas and islet transplantation have been shown to normalize glucose levels but require lifelong [[immunosuppression]] to prevent graft rejection and recurrence of autoimmune islet destruction. although, islet cell transplantation remains investigational. [[Pancreas transplantation]] is considered for patients with chronic diabetes and multiple complications.<br> | ||
Indication for pancreas transplantation is:<ref name="pmid16567844">{{cite journal |vauthors=Robertson RP, Davis C, Larsen J, Stratta R, Sutherland DE |title=Pancreas and islet transplantation in type 1 diabetes |journal=Diabetes Care |volume=29 |issue=4 |pages=935 |year=2006 |pmid=16567844 |doi= |url=}}</ref> | Indication for pancreas transplantation is:<ref name="pmid16567844">{{cite journal |vauthors=Robertson RP, Davis C, Larsen J, Stratta R, Sutherland DE |title=Pancreas and islet transplantation in type 1 diabetes |journal=Diabetes Care |volume=29 |issue=4 |pages=935 |year=2006 |pmid=16567844 |doi= |url=}}</ref> | ||
*Patients who have history of frequent severe metabolic derangement (hypoglycemia, marked hyperglycemia, ketoacidosis), intolerant to exogenous insulin therapy or failure of treatment with insulin. | *Patients who have history of frequent severe metabolic derangement ([[hypoglycemia]], marked [[hyperglycemia]], [[ketoacidosis]]), intolerant to exogenous insulin therapy or failure of treatment with insulin. | ||
==References== | ==References== | ||
{{Reflist|2}} | {{Reflist|2}} |
Revision as of 16:01, 30 March 2017
Diabetes mellitus type 2 Microchapters |
Differentiating Diabetes Mellitus Type 2 from other Diseases |
Diagnosis |
Treatment |
Medical therapy |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Seyedmahdi Pahlavani, M.D. [2]
Overview
Pancreas and islet cell transplantation is considered in patients with chronic diabetes who have frequent metabolic complications and are intolerant to exogenous insulin or have failed to insulin therapy.
Surgery
There is no indication for surgery in type 2 diabetes mellitus unless, there is an indication for pancreas and islet cell transplantation. Pancreas and islet transplantation have been shown to normalize glucose levels but require lifelong immunosuppression to prevent graft rejection and recurrence of autoimmune islet destruction. although, islet cell transplantation remains investigational. Pancreas transplantation is considered for patients with chronic diabetes and multiple complications.
Indication for pancreas transplantation is:[1]
- Patients who have history of frequent severe metabolic derangement (hypoglycemia, marked hyperglycemia, ketoacidosis), intolerant to exogenous insulin therapy or failure of treatment with insulin.