Thrombotic thrombocytopenic purpura surgery

Thrombotic thrombocytopenic purpura Microchapters
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2]

Overview

The mainstay of treatment for TTP is medical therapy. Surgery is usually reserved for patients with either no cure with plasma treatments and medicines.

Indications

• Surgery is not the first line treatment option for patients withTTP when plasma treatments(PEX) and medicines do not cure TTP, surgery is needed.

Surgery

• Surgery is not the first-line treatment option for patients withTTP. Sometimes splenectomy is needed, because the antibodies is made by cell in spleen that block ADAMTS13 enzyme activity.