Pre-eclampsia diagnostic study of choice

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sara Zand, M.D.[2] Ogheneochuko Ajari, MB.BS, MS [3]

Overview

The diagnosis of preeclampsia is made when at least two of the following three diagnostic criteria are met: 1.Blood pressure (Systolic blood pressure of 140 mm Hg or more or diastolic blood pressure of 90 mm Hg or more) on two occasions at least 4 hours apart after 20 weeks of gestation in a woman with a previously normal blood pressure, systolic blood pressure of 160 mm Hg or more or diastolic blood pressure of 110 mm Hg or more, 2.Proteinuria (300 mg or more per 24-hour urine collection or Protein/creatinine ratio of 0.3 mg/dL or more or Dipstick of 2+), 3. Or in the absence of proteinuria, new-onset hypertension with the new onset of any of the following: thrombocytopenia: platelet count< 100,000/dl, renal insufficiency: serum creatinine>1.1 mg/dL or a doubling of the serum creatinine concentration in the absence of other renal disease, impaired liver function: elevated blood level of liver transaminases to a twice normal level, pulmonary edema, intractable headache or visual symptoms.

Diagnosis

• Diagnostic Criteria
• The diagnosis of preeclampsia is made when at least two of the following three diagnostic criteria are met:
• 1.Blood pressure

• Systolic blood pressure of 140 mm Hg or more or diastolic blood pressure of 90 mm Hg or more on two occasions at least 4 hours apart after 20 weeks of gestation in a woman with a previously normal blood pressure
• Systolic blood pressure of 160 mm Hg or more or diastolic blood pressure of 110 mm Hg or more.

• 2. Proteinuria

• 300 mg or more per 24-hour urine collection or Protein/creatinine ratio of 0.3 mg/dL or more or Dipstick of 2+

• 3. Or in the absence of proteinuria, new-onset hypertension with the new onset of any of the following:

• Thrombocytopenia: Platelet count< 100,000/dl
• Renal insufficiency: Serum creatinine>1.1 mg/dL or a doubling of the serum creatinine concentration in the absence of other renal disease
• Impaired liver function: Elevated blood level of liver transaminases to a twice normal level
• Pulmonary edema
• Intractable headache or visual symptoms