Odynophagia natural history, complications and prognosis

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Odynophagia Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Odynophagia from other Conditions

Epidemiology and Demographics

Screening

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Natural History, Complications and Prognosis

Diagnosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Overview

If left untreated, patients with odynophagia may progress to develop weight loss, malnutrition, and food aversion. Prognosis is generally excellent, and the mortality/survival rate of patients with odynophagia depend on the primary cause.

Natural History, Complications, and Prognosis

Natural History

  • If left untreated, patients with odynophagia may progress to develop weight loss, malnutrition, and food aversion.
  • However the causes of odynophagia have their own independent course of progression and complication. 

Complications

Prognosis

  • Prognosis is generally excellent, and the mortality/survival rate of patients with odynophagia depend on the primary cause.
    • Tumors: Depending on the extent of the tumor at the time of diagnosis, the prognosis may vary. Adenocarcinoma has better prognosis compared to squamous cell cancers.
    • URTI: Prognosis is generally excellent. Viral URTI's have better outcomes compared to bacterial URTI's.
    • GERD: Prognosis is generally good. If untreated 20% may develop esophageal strictures.[1]
    • Foreign body: Prognosis is generally excellent, if foreign body is removed in a timely manner.
    • Esophagitis: Prognosis is generally good. It depends mostly on the cause of esophageal inflammation. Viral infections recover earlier with less complications compared to autoimmune, bacterial and chemical causes.

References

  1. Sonnenberg A, El-Serag HB (1999). "Clinical epidemiology and natural history of gastroesophageal reflux disease". Yale J Biol Med. 72 (2–3): 81–92. PMC 2579001. PMID 10780569.

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