Multiple pulmonary nodules

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Pulmonary Nodule Microchapters


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Differentiating Pulmonary Nodule from Other Diseases

Epidemiology and Demographics


Natural history, Complications and Prognosis


Evaluation of Solitary Pulmonary Nodule

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2] Luke Rusowicz-Orazem, B.S.


Common causes of multiple pulmonary nodules include pulmonary neoplasms and tumor metastasis from outside of the lungs. These causes are life-threatening and should be promptly differentiated from benign neoplasms and non-fatal infectious causes. Additional life threatening causes that present with multiple pulmonary nodules include cardio-pulmonary conditions, such as aneurysm and infarction. Additional causes include granulomas.


Life Threatening Causes

Common Causes[1]

Causes by Organ System

Cardiovascular Aneurysm of the pulmonary artery, Arteriovenous malformation, Infarction zone, Pulmonary arterio-venous malformation, Pulmonary embolism, Pulmonary infarction, Varicose pulmonary vein, Vascular
Chemical/Poisoning No underlying causes
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect No underlying causes
Ear Nose Throat No underlying causes
Endocrine Non-hodgkin lymphoma, Thyroid cancer
Environmental Black lung disease
Gastroenterologic Gastric cancer
Genetic No underlying causes
Hematologic Aneurysm of the pulmonary artery, Hemangioma, Hematoma, Non-hodgkin lymphoma, Pulmonary hamartoma
Iatrogenic No underlying causes
Infectious Disease Bronchogenic carcinoma
Musculoskeletal/Orthopedic Multiple myeloma
Neurologic Aneurysm of the pulmonary artery, Arteriovenous malformation, Neurofibroma, Neurogenic tumor
Nutritional/Metabolic No underlying causes
Obstetric/Gynecologic Breast cancer
Oncologic Adenocarcinoma , Blastoma, Breast cancer, Bronchial adenoma, Bronchogenic carcinoma, Cancers, Carcinoid tumor, Chondroma, Gastric cancer, Granuloma, Hamartoma, Hamartomatosis, Hemangioma, Hematoma, Hypernephroma, Large cell lung carcinoma, Lymphoma, Metastasis, Multiple myeloma, Neurogenic tumor, Non-hodgkin lymphoma, Non-small cell lung cancer, Primary lung cancer, Prostate cancer, Pulmonary sarcoma, Sarcoma, Seminoma, Small cell lung cancer, Squamous cell carcinoma, Thyroid cancer
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric No underlying causes
Pulmonary Amyloidosis, Aneurysm of the pulmonary artery, Black lung disease, Bronchial adenoma, Bronchogenic carcinoma, Infarction zone, Large cell lung carcinoma, Lung abscess, Lung cavity, Lung metastases, Non-small cell lung cancer, Primary lung cancer, Pulmonary arterio-venous malformation, Pulmonary embolism, Pulmonary infarction, Pulmonary sarcoma, Sarcoidosis, Small cell lung cancer, Varicose pulmonary vein, Vascular, Wegener's granulomatosis
Renal/Electrolyte Hypernephroma
Rheumatology/Immunology/Allergy Amyloidosis, Churg-strauss syndrome, Fibroma, Granuloma, Hamartoma, Immunological, Neurofibroma, Progressive massive fibrosis, Rheumatoid arthritis, Rheumatoid disease, Sarcoidosis, Wegener's granulomatosis
Sexual No underlying causes
Urologic Prostate cancer
Miscellaneous No underlying causes

Causes in Alphabetical Order


  1. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002: 306-307 ISBN 1591032016

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