Lipodystrophy

Jump to: navigation, search

WikiDoc Resources for Lipodystrophy

Articles

Most recent articles on Lipodystrophy

Most cited articles on Lipodystrophy

Review articles on Lipodystrophy

Articles on Lipodystrophy in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Lipodystrophy

Images of Lipodystrophy

Photos of Lipodystrophy

Podcasts & MP3s on Lipodystrophy

Videos on Lipodystrophy

Evidence Based Medicine

Cochrane Collaboration on Lipodystrophy

Bandolier on Lipodystrophy

TRIP on Lipodystrophy

Clinical Trials

Ongoing Trials on Lipodystrophy at Clinical Trials.gov

Trial results on Lipodystrophy

Clinical Trials on Lipodystrophy at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Lipodystrophy

NICE Guidance on Lipodystrophy

NHS PRODIGY Guidance

FDA on Lipodystrophy

CDC on Lipodystrophy

Books

Books on Lipodystrophy

News

Lipodystrophy in the news

Be alerted to news on Lipodystrophy

News trends on Lipodystrophy

Commentary

Blogs on Lipodystrophy

Definitions

Definitions of Lipodystrophy

Patient Resources / Community

Patient resources on Lipodystrophy

Discussion groups on Lipodystrophy

Patient Handouts on Lipodystrophy

Directions to Hospitals Treating Lipodystrophy

Risk calculators and risk factors for Lipodystrophy

Healthcare Provider Resources

Symptoms of Lipodystrophy

Causes & Risk Factors for Lipodystrophy

Diagnostic studies for Lipodystrophy

Treatment of Lipodystrophy

Continuing Medical Education (CME)

CME Programs on Lipodystrophy

International

Lipodystrophy en Espanol

Lipodystrophy en Francais

Business

Lipodystrophy in the Marketplace

Patents on Lipodystrophy

Experimental / Informatics

List of terms related to Lipodystrophy

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:

Lipodystrophy
ICD-10 E88.1
ICD-9 272.6
DiseasesDB 30066
MeSH D008060

Overview

Lipodystrophy is a medical condition characterized by abnormal or degenerative conditions of the body's adipose tissue. ("Lipo" is Latin for "fat" and "dystrophy" is Latin for "abnormal or degenerative condition".) A more specific term, lipoatrophy is used when describing the loss of fat from one area (usually the face).

Insulin injections

A lipodystrophy can be a lump or small dent in the skin that forms when a person keeps performing injections in the same spot. These types of lipodystrophies are harmless. People who want to avoid them can do so by changing (rotating) the places where they perform injections. For people with diabetes, using purified insulins may also help.

One of the side-effects of lipodystrophy is the rejection of the injected medication, the slowing down of the absorption of the medication, or trauma that can cause bleeding that, in turn, will reject the medication. In either scenarios, the dosage of the medication, such as insulin for diabetics, becomes impossible to gauge correctly and the treatment of the disease for which the medication is administered is impaired thereby allowing the medical condition to worsen.

In some cases, rotation of the injection sites may not be enough to prevent lipodystrophy.

Antiretroviral drugs

Lipodystrophies can be a possible side effect of antiretroviral drugs such as Dolutegravir, lamivudine, Rilpivirine, Ritonavir, Saquinavir mesylate. Other lipodystrophies manifest as lipid redistribution; with excess, or lack of, fat in various regions of the body. These include, but are not limited to, having sunken cheeks and/or "humps" on the back or back of the neck (also referred to as buffalo hump).[1]

Hereditary form

Lipodystrophy can be caused by metabolic abnormalities due to genetic issues. These are often characterized by insulin resistance and are associated with Syndrome X.

See also

External links

References

  1. Physical and Biochemical Changes in HIV Disease Eric S. Daar, M.D. MedicineNet, Accessed 22 September 2007

de:Lipodystrophie nl:Lipodystrofie



Linked-in.jpg