Linitis plastica natural history

Jump to: navigation, search

Linitis plastica Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Linitis plastica from Other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Staging

Diagnostic study of choice

Physical Examination

Laboratory Findings

Electrocardiogram

X-ray

Echocardiography and Ultrasound

CT

MRI

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Linitis plastica natural history On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Linitis plastica natural history

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Linitis plastica natural history

CDC on Linitis plastica natural history

Linitis plastica natural history in the news

Blogs on Linitis plastica natural history

Directions to Hospitals Treating Linitis plastica

Risk calculators and risk factors for Linitis plastica natural history

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Soujanya Thummathati, MBBS [2]

Overview

If left untreated, patients with linitis plastica may progress to develop symptoms from decreased peristalsis of the stomach that may include dyspepsia, dysphagia, nausea, vomiting, increased satiety, and regurgitation.[1][2] Depending upon the stage of linitis plastica at the time of diagnosis, the prognosis may vary. The presence of metastasis is associated with a particularly poor prognosis among patients with linitis plastica. Linitis plastica is associated with a 5-year survival rate of approximately 10-20% in Japan.[2]

Natural history

Patients are usually asymptomatic in the initial stages of the disease. If left untreated, patients with linitis plastica may progress to develop symptoms from decreased peristalsis of the stomach and may include dyspepsia, dysphagia, nausea, vomiting, increased satiety, and regurgitation.[1][2]

Complications

Patients with linitis plastica may progress to develop gastric outlet obstruction from the rigid stomach wall that limits the process of digestion.[3]

Prognosis

Depending upon the stage of linitis plastica at the time of diagnosis, the prognosis may vary. The presence of metastasis is associated with a particularly poor prognosis among patients with linitis plastica because of the rapid peritoneal and lymphatic spread of the disease. Linitis plastica is associated with a 5-year survival rate of approximately 10-20% in Japan.[2]

References

  1. 1.0 1.1 Jafferbhoy S, Shiwani H, Rustum Q (2013). "Managing Gastric Linitis Plastica: Keep the scalpel sheathed". Sultan Qaboos Univ Med J. 13 (3): 451–3. PMC 3749031. PMID 23984032.
  2. 2.0 2.1 2.2 2.3 Gastric linitis plastica. Orphanet. http://www.orpha.net/consor/cgi-bin/OC_Exp.php?Lng=GB&Expert=36273 Accessed on November 19, 2015.
  3. Shiver SA, Blaivas M (2004). "Gastric outlet obstruction secondary to linitis plastica of the stomach as shown on transabdominal sonography". J Ultrasound Med. 23 (7): 989–92. PMID 15292571.



Linked-in.jpg