Linitis plastica screening

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Hadeel Maksoud M.D.[2]

Overview

There is insufficient evidence to recommend routine screening for linitis plastica. However, for familial cases of inherited diffuse gastric cancer, genetic screening for CDH1 gene mutation is available.

Screening

  • There is insufficient evidence to recommend routine screening for linitis plastica.[1]
  • However, for familial cases of inherited diffuse gastric cancer genetic screening for CDH1 gene mutation is available.
  • Screening for gastric cancers is usually carried out via endoscopic biopsy, however, in the case of linitis plastica, barium study may be more effective than endoscopy. The indistensibility of the gastric wall is detected easily with barium.

References

  1. Longo WE, Zucker KA, Zdon MJ, Modlin IM (1989). "Detection of early gastric cancer in an aggressive endoscopy unit". Am Surg. 55 (2): 100–4. PMID 2916797.