Large cell carcinoma of the lung causes
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Maria Fernanda Villarreal, M.D. [2]
Overview
Common causes of large cell carcinoma of lung include smoking, asbestos exposure, ionizing radiation, atmospheric pollution, and chronic interstitial pneumonitis. Less common causes of large cell carcinoma of the lung include chromium and nickel exposure, vinyl chloride exposure, and inorganic arsenic exposure.
Common Causes
- There are no precursor lesions associated with most of the types of large cell carcinoma except for basaloid carcinoma.[1]
- Smoking (active/passive)
- Asbestos exposure
- Chronic interstitial pneumonitis
- Ionizing radiation
- Atmospheric pollution
Less Common Causes
- Inorganic arsenic exposure
- Chromium, nickel exposure
- Vinyl chloride exposure
- Radon exposure
- Halogen ether exposure
References
- ↑ Muscat JE, Stellman SD, Zhang ZF, Neugut AI, Wynder EL (July 1997). "Cigarette smoking and large cell carcinoma of the lung". Cancer Epidemiol. Biomarkers Prev. 6 (7): 477–80. PMID 9232332.
- ↑ 2.0 2.1 National Cancer Institute: PDQ® Non-Small Cell Lung Cancer Treatment. Bethesda, MD: National Cancer Institute. Date last modified January 22. http://www.cancer.gov/types/lung/hp/non-small-cell-lung-treatment-pdq. Accessed February 23, 2015
- ↑ Fasano M, Della Corte CM, Papaccio F, Ciardiello F, Morgillo F (August 2015). "Pulmonary Large-Cell Neuroendocrine Carcinoma: From Epidemiology to Therapy". J Thorac Oncol. 10 (8): 1133–41. doi:10.1097/JTO.0000000000000589. PMC 4503246. PMID 26039012.
- ↑ Barbone F, Bovenzi M, Cavallieri F, Stanta G (December 1997). "Cigarette smoking and histologic type of lung cancer in men". Chest. 112 (6): 1474–9. PMID 9404741.