Lansoprazole detailed information

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Lansoprazole detailed information
File:Lansoprazole 3D.png
Clinical data
[[Regulation of therapeutic goods |Template:Engvar data]]
  • AU: B3
  • US: B (No risk in non-human studies)
Routes of
Oral, IV
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability80% or more
Protein binding97%
MetabolismHepatic (CYP3A4- and CYP2C19-mediated)
Elimination half-life1–1.5 hours
ExcretionRenal and fecal
CAS Number
PubChem CID
E number{{#property:P628}}
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Chemical and physical data
Molar mass369.363 g/mol
3D model (JSmol)

Lansoprazole (lan-SOE-pra-zole, INN) is a proton pump inhibitor which prevents the stomach from producing acid. It is manufactured by a number of companies worldwide under several trade names. It was first approved by the FDA in 1995 [1].


Lansoprazole is a proton pump inhibitor (PPI) in the same pharmacologic class as omeprazole. Lansoprazole has been marketed for many years and is one of several PPI's available.[citation needed]

Lansoprazole's plasma elimination half-life is not proportional to the duration of the drug's effects (i.e. gastric acid suppression). The mean plasma elimination half-life is 1.5 hours,[1] and the effects of the drug last for over 24 hours after it has been used for 1 day or more.[citation needed]


Lansoprazole is indicated for:

Drug Interactions

Side effects

Brand names

Prevacid 30 mg

The drug is sold under several brand names, including: [2]

  • Aprazol (Turkey)
  • Duogast (Syria)
  • Lanpro (India)
  • Lansox (Italy)
  • Lanton (Israel)
  • Lanzor (France)
  • Laprazol (Greece)
  • Limpidex (Italy)
  • Ogast and OgastORO (France)
  • Prevacid (U.S. and Canada) Prevacid is a product of TAP Pharmaceutical Products.
  • Prosogan and Prosogan FD (Indonesia)
  • Refluxon (Hungary)
  • SOLOX (New Zealand)
  • Takepron (Japan)
  • Zoton (Italy, Ireland, Australia, UK)

Lansoprazole is also available as a generic drug in the UK, Belgium, France, Colombia, Italy and Mexico.


  1. 1.0 1.1 "Prevacid Pharmacology, Pharmacokinetics, Studies, Metabolism". 2007. Retrieved 2007-04-14.

External links

Template:Proton-Pump Inhibitors

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