Hypercalcemia natural history, complications and prognosis
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Hypercalcemia On the Web
American Roentgen Ray Society Images of Hypercalcemia
Editor-In-Chief: C. Michael Gibson, M.S., M.D. ; Associate Editor(s)-in-Chief: Anmol Pitliya, M.B.B.S. M.D.
Mild hypercalcemia is usually asymptomatic and goes undetected in a large number of patients. Furthermore, it commonly reflects in routine laboratory exams. Hypercalcemia may complicated various organ systems including renal (most commonly), gastrointestinal, and skelatal. Prognosis of hypercalcemia is usually excellent after treatment.
Natural History, Complications, and Prognosis
- Mild hypercalcemia is usually asymptomatic and goes undetected in a large number of patients.
- Hypercalcemia may present in any age group depending on etiology and severity and presents initially with concentration and sleep abnormalities.
Possible complications include:
- Calcium deposits in the kidney (nephrocalcinosis)
- High blood pressure
- Kidney failure
- Kidney stones
- Difficulty concentrating or thinking
- Bone cysts
These complications of long-term hypercalcemia are uncommon today.
- Prognosis of hypercalcemia is usually excellent after treatment.
- However, untreated hypercalcemia may be fatal.
- ↑ 1.0 1.1 Shane, Elizabeth & Irani, Dinaz. (2006). Chapter 26. Hypercalcemia: Pathogenesis, Clinical Manifestations, Differential Diagnosis, and Management. Primer on the metabolic bone diseases and disorders of mineral metabolism.
- ↑ Corlew DS, Bryda SL, Bradley EL, DiGirolamo M (1985). "Observations on the course of untreated primary hyperparathyroidism". Surgery. 98 (6): 1064–71. PMID 3878002.