Familial mediterranean fever epidemiology and demographics
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The incidence of familial mediterranean fever is estimated 100 per 100,000 individuals worldwide. The prevalence of familial mediterranean fever differs widely according to the geographic area. In the non- Ashkenazi Jews, it ranges from 100 to 400 per 100,000 individuals. Patients of all age groups may develop the familial Mediterranean fever (FMF). However, it usually manifests during childhood. This disorder usually affects individuals of the Turkish, Armenian, Jewish and Arabic communities. However, it is also common among western societies such as Italy, Greece, Crete, France, and Germany.
Epidemiology and Demographics
- The incidence of familial mediterranean fever is estimated 100 per 100,000 individuals worldwide. but it has been claimed that it varies according to the ethnicity.
- The prevalence of familial mediterranean fever differs widely according to geographic area.
- In the non- Ashkenazi Jews, it ranges from 100 to 400 per 100,000 individuals.
- In Turkey, it ranges from 93 to 253 per 100,000 individuals.
- Patients of all age groups may develop the familial Mediterranean fever (FMF). However, it usually manifests during childhood.
- 90% of the individuals present the symptoms before the age of 20 years.
- Only 1% of individuals present the first symptoms after the 40 years of age. However, this may vary according to the geographical area of the study.
- The majority of FMF cases are reported among the nations of the Mediterranean region.
- This disorder is most commonly seen in Turkey, followed by Armenia.
- Among western countries, Italy has one of the highest prevalence of FMF.
- FMF cases has also been reported in in other Mediterranean countries like Greece, Crete, France, and Germany.
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