FEV1/FVC ratio

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

The FEV1/FVC ratio is a calculated ratio used in the diagnosis of obstructive and restrictive lung disease.

It represents the proportion of the forced vital capacity exhaled in the first second.[1]

Disease States

In obstructive lung disease, the FEV1 is reduced due to obstruction to air escape. Thus, the FEV1/FVC ratio will be reduced.[2]

In restrictive lung disease, the FEV1 and FVC are equally reduced due to fibrosis or other lung pathology (not obstructive pathology). Thus, the FEV1/FVC ratio should be approximately normal.[3]

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