Coronavirus other diagnostic studies
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Overview
Research laboratories have used isolation methods, electron microscopy, serology and PCR-based assays to diagnose coronavirus infections for surveillance studies.
Other Diagnostic Studies
Specific laboratory tests may include:
- Virus isolation in cell culture.
- Polymerase chain reaction (PCR) assays that are more practical and available commercially.
- Serological testing for antibodies to human coronaviruses.
Nose and throat swabs are the best specimens for detecting common human coronaviruses. Serological testing requires collection of blood specimens.
Gallery
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![SEM reveals the “rosette-like” appearance of the matured coronavirus particles. From Public Health Image Library (PHIL). [1]](/images/2/25/Coronavirus21.jpeg)
SEM reveals the “rosette-like” appearance of the matured coronavirus particles. From Public Health Image Library (PHIL). [1] -
![TEM revealed the presence of a number of infectious bronchitis virus (IBV) virions. From Public Health Image Library (PHIL). [1]](/images/c/cc/Coronavirus20.jpeg)
TEM revealed the presence of a number of infectious bronchitis virus (IBV) virions. From Public Health Image Library (PHIL). [1] -
![Scanning electron micrograph reveals the prolific exportation of virus particles at the pseudopodial and cell surfaces. From Public Health Image Library (PHIL). [1]](/images/2/2a/Coronavirus18.jpeg)
Scanning electron micrograph reveals the prolific exportation of virus particles at the pseudopodial and cell surfaces. From Public Health Image Library (PHIL). [1] -
![Scanning electron micrograph reveals the prolific exportation of virus particles at the pseudopodial and cell surfaces. From Public Health Image Library (PHIL). [1]](/images/5/52/Coronavirus16.jpeg)
Scanning electron micrograph reveals the prolific exportation of virus particles at the pseudopodial and cell surfaces. From Public Health Image Library (PHIL). [1] -
![TEM from a tissue culture isolate, revealing numbers of severe acute respiratory virus (SARS) virions. From Public Health Image Library (PHIL). [1]](/images/4/4a/Coronavirus15.jpeg)
TEM from a tissue culture isolate, revealing numbers of severe acute respiratory virus (SARS) virions. From Public Health Image Library (PHIL). [1]
![SEM reveals the “rosette-like” appearance of the matured coronavirus particles. From Public Health Image Library (PHIL). [1]](/index.php/File:Coronavirus21.jpeg)
![TEM revealed the presence of a number of infectious bronchitis virus (IBV) virions. From Public Health Image Library (PHIL). [1]](/index.php/File:Coronavirus20.jpeg)
![Scanning electron micrograph reveals the prolific exportation of virus particles at the pseudopodial and cell surfaces. From Public Health Image Library (PHIL). [1]](/index.php/File:Coronavirus18.jpeg)
![Scanning electron micrograph reveals the prolific exportation of virus particles at the pseudopodial and cell surfaces. From Public Health Image Library (PHIL). [1]](/index.php/File:Coronavirus16.jpeg)
![TEM from a tissue culture isolate, revealing numbers of severe acute respiratory virus (SARS) virions. From Public Health Image Library (PHIL). [1]](/index.php/File:Coronavirus15.jpeg)