Acute viral nasopharyngitis historical perspective
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Common cold was first considered a distinct diagnosis by Benjamin Franklin in the 18th century.
- In the 18th century, Benjamin Franklin considered the causes and prevention of the common cold.
- After several years of research, he concluded that "People often catch a cold from one another when shut up together in small close rooms, or coaches; and when sitting near and conversing, so as to breathe in each other's transpiration."
- Although viruses had not yet been discovered, Franklin hypothesized that the common cold was passed between people through the air.
- He recommended exercise, bathing, and moderation in food and drink consumption to avoid the common cold. Franklin's theory on the transmission of the cold was confirmed about 150 years later.
Common Cold Unit (CCU)
- In the United Kingdom, the Common Cold Unit (CCU) was set up by the civilian Medical Research Council in 1946. The unit worked with volunteers who were infected with various viruses.
- The rhinovirus was discovered in the CCU in the 1950s; scientists were able to culture the virus on a tissue culture.
- In the 1970s, the CCU proved that using interferon during the incubation period could be potentially protective against developing the infection.
- In 1987, the unit completed its research on zinc gluconate lozenges for prophylaxis against rhinovirus.
- In 1989, the unit was closed.
- "Scientist and Inventor: Benjamin Franklin: In His Own Words... (AmericanTreasures of the Library of Congress)".
- Andrewes CH, Lovelock JE, Sommerville T (1951). "An experiment on the transmission of colds". Lancet. 1 (1): 25–7. PMID 14795755.
- Reto U. Schneider (2004). Das Buch der verrückten Experimente (Broschiert). ISBN 344215393X.
- Al-Nakib W, Higgins PG, Barrow I, Batstone G, Tyrrell DA (1987). "Prophylaxis and treatment of rhinovirus colds with zinc gluconate lozenges". J Antimicrob Chemother. 20 (6): 893–901. PMID 3440773.
- Tyrrell DA (1992). "A view from the Common Cold Unit". Antiviral Res. 18 (2): 105–25. PMID 1329647.