Syncope causes: Difference between revisions

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| '''Drug Side Effect'''
| '''Drug Side Effect'''
|bgcolor="Beige"| [[ACEI|ACE inhibitor]], [[Alfuzosin]], [[alpha blockers]], [[amitriptyline]],  [[Amobarbital sodium]],  [[antiarrhythmics]], [[antidepressants]], [[antiemetics]], [[Antihypertensive|antihypertensive medications]], [[antipsychotic agents]], [[barbiturates]], [[beta blockers]], [[Bicalutamide]], [[bromocriptine]], [[calcium channel blocker]], [[Chlordiazepoxide]], [[chlorpheniramine]], [[cinnarizine]], [[Clomifene]], [[clonidine]], [[clozapine]], [[desipramine]], [[digoxin]], [[diphenhydramine]], [[disulfiram]], [[diuretics]], [[dothiepin]], [[Erectile dysfunction medical therapy|erectile dysfunction medications]], [[Ganglionic blocker|ganglionic blocker]], [[hydralazine]], [[hydroxyzine]], [[Iloperidone]], [[Interferon-gamma]], [[Lacosamide]], [[Levalbuterol]], [[L-dopa]], [[Loxapine]], [[Meropenem]], [[Methocarbamol]], [[Mitomycin]],  [[Nabilone]], [[nabumetone]], [[nitrates]], [[nortriptyline]], [[olanzapine]] [[opiates]], [[orphenadrine]], [[oxazepam]], [[oxcarbazepine]], [[Pentamidine]], [[Pergolide]], [[prednisolone]], [[Isethionate]], [[phenothiazines]], [[rifaximin]], [[Ritonavir]], [[ropinirole]], [[Rotigotine]], [[Secobarbital sodium]], [[sertraline]], [[Sodium oxybate]], [[sulindac]], [[Tiagabine]], [[tricyclic antidepressants]], [[vasodilators]], [[zolmitriptan]], [[zonisamide]], [[Calcium gluconate]],  [[Cefaclor]]
|bgcolor="Beige"| [[ACEI|ACE inhibitor]], [[Alfuzosin]], [[alpha blockers]], [[amitriptyline]],  [[Amobarbital sodium]],  [[antiarrhythmics]], [[antidepressants]], [[antiemetics]], [[Antihypertensive|antihypertensive medications]], [[antipsychotic agents]], [[barbiturates]], [[beta blockers]], [[Bicalutamide]], [[bromocriptine]], [[calcium channel blocker]], [[Chlordiazepoxide]], [[chlorpheniramine]], [[cinnarizine]], [[Clomifene]], [[clonidine]], [[clozapine]], [[desipramine]], [[digoxin]], [[diphenhydramine]], [[disulfiram]], [[diuretics]], [[dothiepin]], [[Erectile dysfunction medical therapy|erectile dysfunction medications]], [[Ganglionic blocker|ganglionic blocker]], [[hydralazine]], [[hydroxyzine]], [[Iloperidone]], [[Interferon-gamma]], [[Lacosamide]], [[Levalbuterol]], [[L-dopa]], [[Loxapine]], [[Meropenem]], [[Methocarbamol]], [[Mitomycin]],  [[Nabilone]], [[nabumetone]], [[Niacin]], [[nitrates]], [[nortriptyline]], [[olanzapine]] [[opiates]], [[orphenadrine]], [[oxazepam]], [[oxcarbazepine]], [[Pentamidine]], [[Pergolide]], [[prednisolone]], [[Isethionate]], [[phenothiazines]], [[rifaximin]], [[Ritonavir]], [[ropinirole]], [[Rotigotine]], [[Secobarbital sodium]], [[sertraline]], [[Sodium oxybate]], [[sulindac]], [[Tiagabine]], [[tricyclic antidepressants]], [[vasodilators]], [[zolmitriptan]], [[zonisamide]], [[Calcium gluconate]],  [[Cefaclor]]
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*[[Multiple system atrophy]]
*[[Multiple system atrophy]]
*[[Nabilone]]
*[[Nabilone]]
*[[Niacin]]
*[[Nitrates]]
*[[Nitrates]]
*[[Nortriptyline]]
*[[Nortriptyline]]

Revision as of 14:49, 9 February 2015

Syncope Microchapters

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Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Syncope from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Vendhan Ramanujam M.B.B.S [2]

Overview

More serious causes of syncope include cardiac (heart-related) causes such as an abnormal heart rhythm (an arrhythmia), where the heart beats too slowly, too rapidly or too irregularly to pump enough blood to the brain. Other important cardio-vascular conditions that can be manifested by syncope include subclavian steal syndrome and aortic stenosis. Vasovagal (situational) syncope, one of the most common types, may occur in scary or embarrassing situations or during blood drawing, coughing, or urinating

Causes

Peripheral vascular resistance and cardiac output are the two main determinants for the presentation of syncope. autonomic nervous system impairment due to drugs or an autonomic failure, can lead to a decrease in peripheral vascular resistance. Reflex activity impairment may also cause a decrease of peripheral vascular resistance, as the body normal compensation reflexes fail. Decrease in cardiac output may be due to venous pooling, cardioinhibitory reflexes, arrhythmia, hypertension, pulmonary embolism, and volume depletion leading to diminished venous return, among others.

Life threatening Causes

Life-threatening causes include conditions which may result in death or permanent disability within 24 hours if left untreated.

Common Causes

Causes by Organ System

Cardiovascular Acute coronary syndrome, acute myocardial infarction, acute myocarditis, Adams-Stokes syndrome, anomalous origins of coronary arteries, aortic aneurysm, aortic dissection, aortic stenosis, arrhythmogenic right ventricular dysplasia, atrial myxoma, atrioventricular block, AV nodal reentrant tachycardia, bifascicular block, bradyarrhythmia, brugada syndrome, cardiac tamponade, catecholaminergic polymorphic ventricular tachycardia, channelopathy, complete atrioventricular block, dehydration, dilated cardiomyopathy, epsilon wave, hemorrhage, hypertrophic cardiomyopathy, hypotension, Jervell and Lange-Nielsen syndrome, long QT syndrome, mitral stenosis,Meprobamate, orthostatic hypotension, paroxysmal ventricular tachycardia, persistent atrial flutter, preexcitation syndrome, prolonged corrected QT interval, pulmonic stenosis, retroperitoneal hemorrhage, ruptured abdominal aortic aneurysm, saddle embolus, second degree AV block, short corrected QT interval, short QT syndrome, sick sinus syndrome, significant sinus pause, subclavian steal syndrome, supraventricular tachyarrhythmia, third degree heart block, ventricular arrhythmia, ventricular tachycardia, Wolff-Parkinson-White syndrome
Chemical/Poisoning Carbon monoxide, cocaine, ethanol
Dental No underlying causes
Dermatologic No underlying causes
Drug Side Effect ACE inhibitor, Alfuzosin, alpha blockers, amitriptyline, Amobarbital sodium, antiarrhythmics, antidepressants, antiemetics, antihypertensive medications, antipsychotic agents, barbiturates, beta blockers, Bicalutamide, bromocriptine, calcium channel blocker, Chlordiazepoxide, chlorpheniramine, cinnarizine, Clomifene, clonidine, clozapine, desipramine, digoxin, diphenhydramine, disulfiram, diuretics, dothiepin, erectile dysfunction medications, ganglionic blocker, hydralazine, hydroxyzine, Iloperidone, Interferon-gamma, Lacosamide, Levalbuterol, L-dopa, Loxapine, Meropenem, Methocarbamol, Mitomycin, Nabilone, nabumetone, Niacin, nitrates, nortriptyline, olanzapine opiates, orphenadrine, oxazepam, oxcarbazepine, Pentamidine, Pergolide, prednisolone, Isethionate, phenothiazines, rifaximin, Ritonavir, ropinirole, Rotigotine, Secobarbital sodium, sertraline, Sodium oxybate, sulindac, Tiagabine, tricyclic antidepressants, vasodilators, zolmitriptan, zonisamide, Calcium gluconate, Cefaclor
Ear Nose Throat No underlying causes
Endocrine No underlying causes
Environmental No underlying causes
Gastroenterologic Gastrointestinal bleeding
Genetic Channelopathy
Hematologic No underlying causes
Iatrogenic No underlying causes
Infectious Disease No underlying causes
Musculoskeletal/Orthopedic No underlying causes
Neurologic Carotid sinus hypersensitivity, dysautonomia, Lewy body dementia, multiple system atrophy, parkinson disease, seizure, spinal cord injury, subarachnoid hemorrhage, transient ischemic attack, vagal stimulation, vertebrobasilar insufficiency
Nutritional/Metabolic No underlying causes
Obstetric/Gynecologic No underlying causes
Oncologic Atrial myxoma, carcinoid syndrome
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric Anorexia nervosa, anxiety, emotional stress, hysterical faint, psychogenic pseudosyncope
Pulmonary Hypoxia
Renal/Electrolyte Uremia
Rheumatology/Immunology/Allergy Anaphylaxis, Takayasu's arteritis
Sexual No underlying causes
Trauma No underlying causes
Urologic No underlying causes
Miscellaneous Breath holding spells, choking game, cough, defecation, deglutition, drop attack, hair combing, heat illness, hyperventilation, hypocapnia, hypoglycemia, implanted cardioverter defibrillator malfunction, laughing, micturition, post-exercise, postprandial hypotension, prolonged bed rest, sneeze, significant blood loss, valsalva maneuver, vomiting, weightlifting

Causes in Alphabetical Order

References

  1. Khoo, C.; Chakrabarti, S.; Arbour, L.; Krahn, AD. (2013). "Recognizing life-threatening causes of syncope". Cardiol Clin. 31 (1): 51–66. doi:10.1016/j.ccl.2012.10.005. PMID 23217687. Unknown parameter |month= ignored (help)
  2. Kapoor, WN. (2000). "Syncope". N Engl J Med. 343 (25): 1856–62. doi:10.1056/NEJM200012213432507. PMID 11117979. Unknown parameter |month= ignored (help)
  3. Nishida, K.; Hirota, SK.; Tokeshi, J. (2008). "Laugh syncope as a rare sub-type of the situational syncopes: a case report". J Med Case Rep. 2: 197. doi:10.1186/1752-1947-2-197. PMID 18538031.
  4. Benbadis, SR.; Chichkova, R. (2006). "Psychogenic pseudosyncope: an underestimated and provable diagnosis". Epilepsy Behav. 9 (1): 106–10. doi:10.1016/j.yebeh.2006.02.011. PMID 16697264. Unknown parameter |month= ignored (help)


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