Primary hyperaldosteronism CT scan Findings: Difference between revisions
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==Overview== | ==Overview== | ||
CT scan may aid in visualizing adrenal adenomas for lesions that are amenable to surgery.<ref name="pmid25002246">{{cite journal |vauthors=Kline GA, Dias VC, So B, Harvey A, Pasieka JL |title=Despite limited specificity, computed tomography predicts lateralization and clinical outcome in primary aldosteronism |journal=World J Surg |volume=38 |issue=11 |pages=2855–62 |year=2014 |pmid=25002246 |doi=10.1007/s00268-014-2694-9 |url=}}</ref><ref name="pmid27325147">{{cite journal |vauthors=Dekkers T, Prejbisz A, Kool LJ, Groenewoud HJ, Velema M, Spiering W, Kołodziejczyk-Kruk S, Arntz M, Kądziela J, Langenhuijsen JF, Kerstens MN, van den Meiracker AH, van den Born BJ, Sweep FC, Hermus AR, Januszewicz A, Ligthart-Naber AF, Makai P, van der Wilt GJ, Lenders JW, Deinum J |title=Adrenal vein sampling versus CT scan to determine treatment in primary aldosteronism: an outcome-based randomised diagnostic trial |journal=Lancet Diabetes Endocrinol |volume=4 |issue=9 |pages=739–46 |year=2016 |pmid=27325147 |doi=10.1016/S2213-8587(16)30100-0 |url=}}</ref> | CT scan may aid in visualizing [[Adrenal gland|adrenal]] [[adenomas]] for lesions that are amenable to surgery.<ref name="pmid25002246">{{cite journal |vauthors=Kline GA, Dias VC, So B, Harvey A, Pasieka JL |title=Despite limited specificity, computed tomography predicts lateralization and clinical outcome in primary aldosteronism |journal=World J Surg |volume=38 |issue=11 |pages=2855–62 |year=2014 |pmid=25002246 |doi=10.1007/s00268-014-2694-9 |url=}}</ref><ref name="pmid27325147">{{cite journal |vauthors=Dekkers T, Prejbisz A, Kool LJ, Groenewoud HJ, Velema M, Spiering W, Kołodziejczyk-Kruk S, Arntz M, Kądziela J, Langenhuijsen JF, Kerstens MN, van den Meiracker AH, van den Born BJ, Sweep FC, Hermus AR, Januszewicz A, Ligthart-Naber AF, Makai P, van der Wilt GJ, Lenders JW, Deinum J |title=Adrenal vein sampling versus CT scan to determine treatment in primary aldosteronism: an outcome-based randomised diagnostic trial |journal=Lancet Diabetes Endocrinol |volume=4 |issue=9 |pages=739–46 |year=2016 |pmid=27325147 |doi=10.1016/S2213-8587(16)30100-0 |url=}}</ref> | ||
==CT scan== | ==CT scan== | ||
Adrenal adenomas may display the following features on CT scanning: | [[Adrenal gland|Adrenal]] [[adenomas]] may display the following features on CT scanning: | ||
*Functional adenomas are homogeneous and hypodense. | *Functional [[adenomas]] are [[homogeneous]] and hypodense. | ||
*The signal intensity may be near to <10 HU. | *The signal intensity may be near to <10 HU. | ||
*No contrast enhancement | *No contrast enhancement | ||
*Non-calcified | *[[Calcification|Non-calcified]] | ||
If CT findings are negative, selective adrenal venous sampling for aldosterone or a dexamethasone suppressed iodocholesterol adrenal scan may identify the tumor. | If CT findings are negative, selective adrenal venous sampling for [[aldosterone]] or a [[dexamethasone]] suppressed iodocholesterol adrenal scan may identify the tumor. | ||
[[Image:Adrenal-aldosteronoma.JPG|200px|alight right|Adrenal adenoma of right adrenal gland, case courtesy of MD Gaspar Alberto, Radiopaedia.org, rID: 14723]] | [[Image:Adrenal-aldosteronoma.JPG|200px|alight right|Adrenal adenoma of right adrenal gland, case courtesy of MD Gaspar Alberto, Radiopaedia.org, rID: 14723]] | ||
Revision as of 14:26, 24 July 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]
Overview
CT scan may aid in visualizing adrenal adenomas for lesions that are amenable to surgery.[1][2]
CT scan
Adrenal adenomas may display the following features on CT scanning:
- Functional adenomas are homogeneous and hypodense.
- The signal intensity may be near to <10 HU.
- No contrast enhancement
- Non-calcified
If CT findings are negative, selective adrenal venous sampling for aldosterone or a dexamethasone suppressed iodocholesterol adrenal scan may identify the tumor.
References
- ↑ Kline GA, Dias VC, So B, Harvey A, Pasieka JL (2014). "Despite limited specificity, computed tomography predicts lateralization and clinical outcome in primary aldosteronism". World J Surg. 38 (11): 2855–62. doi:10.1007/s00268-014-2694-9. PMID 25002246.
- ↑ Dekkers T, Prejbisz A, Kool LJ, Groenewoud HJ, Velema M, Spiering W, Kołodziejczyk-Kruk S, Arntz M, Kądziela J, Langenhuijsen JF, Kerstens MN, van den Meiracker AH, van den Born BJ, Sweep FC, Hermus AR, Januszewicz A, Ligthart-Naber AF, Makai P, van der Wilt GJ, Lenders JW, Deinum J (2016). "Adrenal vein sampling versus CT scan to determine treatment in primary aldosteronism: an outcome-based randomised diagnostic trial". Lancet Diabetes Endocrinol. 4 (9): 739–46. doi:10.1016/S2213-8587(16)30100-0. PMID 27325147.