Primary hyperaldosteronism other imaging findings

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1];Associate Editor(s)-in-Chief: Syed Hassan A. Kazmi BSc, MD [2]

Overview

Iodocholesterol scintigraphy (NP-59 scan) may be helpful in the diagnosis of primary aldosteronism. Findings on an Iodocholesterol scintigraphy (NP-59 scan) suggestive of primary aldosteronism is increased uptake of the adrenal glands.

6 beta- 131I iodomethyl-19-norcholesterol (NP-59), was introduced in 1977 for the diagnosis for primary aldosteronism.
The NP-59 scan is performed with dexamethasone suppression.
It is not very useful in identifying micro adenomas of the adrenals (<1.5 cm).^[1]