Gonadoblastoma natural history, complications and prognosis

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sahar Memar Montazerin, M.D.[2]

Overview

If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3]. Common complications of [disease name] include [complication 1], [complication 2], and [complication 3]. Prognosis is generally excellent after removing the tumor.

Natural History, Complications, and Prognosis

Natural History

• The symptoms of gonadoblastoma usually develop in the first/ second/ third decade of life, and start with symptoms such as ___.
• The symptoms of (disease name) typically develop ___ years after exposure to ___.
• If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

Complications

• Common complications of gonadoblastoma include:
  • Dysgerminoma
  • Seminoma
  • Other gonadal malignancies

Prognosis

• Prognosis is generally excellent if the tumor is removed by the time of diagnosis.
• Depending on the presence of the coexisting germinal tumors at the time of diagnosis, the prognosis may vary.