DNA damage response element gene transcriptions: Difference between revisions

Associate Editor(s)-in-Chief: Henry A. Hoff

"The corepressor complex is recruited to the RNR genes by the sequence-specific DNA-binding protein Crt1, which recognizes the DNA damage response elements (DREs) in the upstream repression sequence (URS) (19, 35)."^[1]

Human genes

Consensus sequences

"A consensus sequence, 5'-TAGCCGCCGRRRR-3' (where R = an unspecified purine nucleoside [A/G],was generated from these data."^[2]

DNA damage response element (DRE) has the consensus sequence TTTCAAT.^[3]

Hypotheses

A1BG has no DNA damage response elements in either promoter.
A1BG is not transcribed by a DNA damage response element.
A DNA damage response element does not participate in the transcription of A1BG.

Samplings

Copying the consensus URS: 5'-TAGCCGCCG-3' and putting the sequence in "⌘F" finds no locations between ZNF497 and A1BG or between ZSCAN22 and A1BG as can be found by the computer programs.

Copying the consensus of the DDRE: 5'-TTTCAAT-3' and putting the sequence in "⌘F" finds no locations for this sequence in any A1BG direction as can be found by the computer programs.

For the Basic programs testing consensus sequence 5'-TTTCAAT-3' (starting with SuccessablesDDRE.bas) written to compare nucleotide sequences with the sequences on either the template strand (-), or coding strand (+), of the DNA, in the negative direction (-), or the positive direction (+), the programs are, are looking for, and found:

negative strand, negative direction, looking for 5'-TTTCAAT-3', 0.
negative strand, positive direction, looking for 5'-TTTCAAT-3', 0.
positive strand, negative direction, looking for 5'-TTTCAAT-3', 0.
positive strand, positive direction, looking for 5'-TTTCAAT-3', 0.
complement, negative strand, negative direction, looking for 5'-AAAGTTA-3', 0.
complement, negative strand, positive direction, looking for 5'-AAAGTTA-3', 0.
complement, positive strand, negative direction, looking for 5'-AAAGTTA-3', 0.
complement, positive strand, positive direction, looking for 5'-AAAGTTA-3', 0.
inverse complement, negative strand, negative direction, looking for 5'-ATTGAAA-3', 0.
inverse complement, negative strand, positive direction, looking for 5'-ATTGAAA-3', 0.
inverse complement, positive strand, negative direction, looking for 5'-ATTGAAA-3', 0.
inverse complement, positive strand, positive direction, looking for 5'-ATTGAAA-3', 0.
inverse negative strand, negative direction, looking for 5'-TAACTTT-3', 0.
inverse negative strand, positive direction, looking for 5'-TAACTTT-3', 0.
inverse positive strand, negative direction, looking for 5'-TAACTTT-3', 0.
inverse positive strand, positive direction, looking for 5'-TAACTTT-3', 0.

Acknowledgements

The content on this page was first contributed by: Henry A. Hoff.

References

↑ Zhengjian Zhang and Joseph C. Reese (17 September 2004). "Redundant Mechanisms Are Used by Ssn6-Tup1 in Repressing Chromosomal Gene Transcription in Saccharomyces cerevisiae". The Journal of Biological Chemistry. 279 (38): 39240–39250. doi:10.1074/jbc.M407159200. PMID 15254041. Retrieved 4 September 2020.
↑ Roberta A. Sumrada and Terrance G. Cooper (June 1987). "Ubiquitous upstream repression sequences control activation of the inducible arginase gene in yeast" (PDF). Proceedings of the National Academy of Sciences USA. 84: 3997–4001. doi:10.1073/pnas.84.12.3997. PMID 3295874. Retrieved 6 September 2020.
↑ Joshua J. Smith, Eric S. Cole, Daniel P. Romero (15 July 2004). "Transcriptional control of RAD51 expression in the ciliate Tetrahymena thermophila". Nucleic Acids Research. 32 (14): 4313–4321. doi:10.1093/nar/gkh771. PMID 15304567. Retrieved 4 September 2020.

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Transcription resources	A1BG gene transcription core promoters A1BG gene transcriptions A1BG regulatory elements and regions A1BG response element gene transcriptions A1BG response element negative results A1BG response element positive results ABA-response element gene transcriptions Abf1 regulatory factor gene transcriptions A box gene transcriptions ACGT-containing element gene transcriptions Activating protein gene transcriptions Activating transcription factor gene transcriptions Adenylate–uridylate rich element gene transcriptions Adr1p gene transcriptions Aft1p gene transcriptions AGC box gene transcriptions AGCE gene transcriptions Alpha-amylase conserved element gene transcriptions Amino acid response element gene transcriptions AARE-like Androgen response element gene transcriptions Angiotensinogen core promoter element gene transcriptions Antioxidant-electrophile responsive element gene transcriptions ATA box gene transcriptions Auxin response factor gene transcriptions B 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gene transcriptions EIN3 binding site gene transcriptions Enhancer activity copy gene transcriptions E box gene transcriptions Element gene transcriptions Endoplasmic reticulum stress response element gene transcriptions Endosperm expression gene transcriptions Enhancer box gene transcriptions Estrogen response element gene transcriptions Ethylene responsive element gene transcriptions Factor II B recognition element gene transcriptions F box gene transcriptions Focused promoter gene transcriptions Forkhead box gene transcriptions Fur box gene transcriptions GAAC element gene transcriptions Gal4p gene transcriptions Γ-interferon activated sequence gene transcriptions GARE gene transcriptions GA responsive complex gene transcriptions GATA gene transcriptions G box gene transcriptions GC box gene transcriptions GCC box gene transcriptions Gcn4p gene transcriptions Gcr1p gene transcriptions Gene expressions General factor II D gene transcriptions General regulatory factors General 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Hybrid C, T boxes Hypoxia-inducible factor gene transcriptions Hypoxia response elements I box gene transcriptions Initiator element gene transcriptions Initiator-like element gene transcriptions Inositol/choline-responsive elements Interaction gene transcriptions Interferon regulatory factors Inverse copy gene transcriptions Jasmonic acid-responsive element gene transcriptions K-boxes Kozak sequence gene transcriptions Kruppel-associated box gene transcriptions Krüppel-like factor gene transcriptions L box gene transcriptions Leu3 gene transcriptions M35 box gene transcriptions MADS box gene transcriptions Maf recognition element gene transcriptions M box gene transcriptions Mcm1 regulatory factor gene transcriptions Met31p box gene transcriptions Metal responsive element gene transcriptions Middle sporulation element gene transcriptions Mig1p gene transcriptions Model samplings Motif ten element gene transcriptions Msn2,4p gene transcriptions Musashi binding element gene transcriptions MYB recognition element gene transcriptions Myelocytomatosis transcription factor gene transcriptions Myocyte enhancer factor gene transcriptions N-boxes Ndt80p gene transcriptions Nuclear factor 1 Nuclear factor 𝜿B Nuclear factor gene transcriptions Nuclear factor of activated T cell gene transcriptions (NFAT) Nuclear factor Y gene transcriptions Nutrient-sensing response element gene transcriptions Oaf1p gene transcriptions ORE1 binding site gene transcriptions p53 response element gene transcriptions P63 DNA-binding site gene transcriptions P box gene transcriptions Pdr1,3p gene transcriptions Peroxisome proliferator hormone response element gene transcriptions Phosphate starvation-response transcription factor gene transcriptions Pollen1 element gene transcriptions Polycomb response element gene transcriptions Preinitiation complex Preinitiation complex gene transcriptions Pribnow box gene transcriptions Prolamin box gene transcriptions Promoter gene transcriptions Proximal promoter gene transcriptions Promoter occurrence gene transcriptions Pyrimidine box gene transcriptions Q element gene transcriptions Rap1 regulatory factor gene transcriptions Reb1 general regulatory factor gene transcriptions Retinoblastoma control element gene transcriptions Retinoic acid response element gene transcriptions Rgt1p gene transcriptions Rlm1p gene transcriptions RNA polymerase II gene transcriptions RNA polymerase II holoenzyme complex Root specific element gene transcriptions ROR-response element gene transcriptions Rox1p gene transcriptions Rpn4p gene transcriptions R response element gene transcriptions SARE gene transcriptions Seed-specific element gene transcriptions Serum response element gene transcriptions Servenius sequence gene transcriptions Shoot specific element gene transcriptions Sip4p gene transcriptions Smp1p gene transcriptions Sp1 gene transcriptions Spaceflight gene expressions Specificity protein gene transcriptions STAT gene transcriptions Ste12p gene transcriptions Sterol response element gene transcriptions Sucrose box gene transcriptions Synaptic Activity-Responsive Elements TACTAAC box gene transcriptions TAGteam gene transcriptions Tapetum box gene transcriptions TATA binding protein associated factor gene transcriptions TATA binding protein gene transcriptions TATA box gene transcriptions TAT box gene transcriptions TATC box gene transcriptions Tbf1 regulatory factor gene transcriptions T box gene transcriptions TCCACCATA element gene transcriptions TC element gene transcriptions TCT gene transcriptions TEA consensus sequence gene transcriptions Tec1p gene transcriptions Telomeric repeat DNA-binding factor gene transcriptions Tetradecanoylphorbol-13-acetate response element gene transcriptions TGF-β control elements (TCEs) TGF-β inhibitory elements (TIEs) Thyroid hormone response element gene transcriptions Transcriptional regulation Transcription bubble gene transcriptions Transcription factor gene transcriptions Transcription factor 3 gene transcriptions Transcription factory gene transcriptions Transcription start site gene transcriptions Translational control sequence gene transcriptions U box gene transcriptions Unfolded protein response element gene transcriptions Upstream response element gene transcriptions Upstream stimulatory factor gene transcriptions UTR promoter gene transcriptions V and P box gene transcriptions V box gene transcriptions Vhr1p gene transcriptions Vitamin D response element gene transcriptions W box gene transcriptions X box gene transcriptions Xbp1p gene transcriptions X core promoter element gene transcriptions Xenobiotic response element gene transcriptions Xenobiotic responsive element gene transcriptions Yap1p,2p gene transcriptions Y box gene transcriptions YY1 gene transcriptions Zap1p gene transcriptions Z box gene transcriptions Zinc responsive element gene transcriptions

@@ Line 75: / Line 75: @@
 # inverse complement, positive strand, negative direction, looking for 5'-ATTGAAA-3', 0.
 # inverse complement, positive strand, positive direction, looking for 5'-ATTGAAA-3', 0.
-# inverse negative strand, negative direction, looking for 5'-AAAAAAAA-3', 0.
+# inverse negative strand, negative direction, looking for 5'-TAACTTT-3', 0.
-# inverse negative strand, positive direction, looking for 5'-AAAAAAAA-3', 0.
+# inverse negative strand, positive direction, looking for 5'-TAACTTT-3', 0.
-# inverse positive strand, negative direction, looking for 5'-AAAAAAAA-3', 0.
+# inverse positive strand, negative direction, looking for 5'-TAACTTT-3', 0.
-# inverse positive strand, positive direction, looking for 5'-AAAAAAAA-3', 0.
+# inverse positive strand, positive direction, looking for 5'-TAACTTT-3', 0.
-=== DDRE core promoters===
-{{main|Core promoter gene transcriptions}}
-=== DDRE proximal promoters===
-{{main|Proximal promoter gene transcriptions}}
-=== DDRE distal promoters===
-{{main|Distal promoter gene transcriptions}}
 ==Acknowledgements==

DNA damage response element gene transcriptions: Difference between revisions

Revision as of 19:31, 18 December 2020

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