Chancroid natural history, complications and prognosis: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
(Created page with "__NOTOC__ {{Chancroid}} Please help WikiDoc by adding content here. It's easy! Click here to learn about editing. ==References== {{Reflist|2...")
 
m (Changes made per Mahshid's request)
 
(23 intermediate revisions by 3 users not shown)
Line 1: Line 1:
__NOTOC__
__NOTOC__
{{Chancroid}}
{{Chancroid}}
{{CMG}}; {{AE}} {{YD}}; {{NRM}}; {{SSK}}


Please help WikiDoc by adding content here. It's easy!  Click  [[Help:How_to_Edit_a_Page|here]] to learn about editing.  
==Overview==
Chancroid symptoms typically develop 4 to 10 days after infection. Initial indication of infection involves formation of erythematous [[papules]] which develop into [[Boil|pustules]] after several days. Approximately 1-2 weeks after pustule formation, the lesions may ulcerate. Patients typically develop 1 to 4 [[ulcers]]. [[Lymphadenopathy]] develops in approximately half of patients, predominantly in males, 1 to 2 weeks after appearance of the primary ulcer. In approximately 25% of patients with lymphadenopathy, lymph nodes may swell to form fluctuant [[Bubo|buboes]] which may rupture and form giant ulcers. Prognosis is poor without treatment. Complications from chancroid include: [[superinfection]] of lesions, extensive [[adenitis]], development of [[inguinal]] [[abscesses]], and nonhealing ulcers.
 
==Natural History==
*The incubation period for ''H. ducreyi'' is typically 4 to 10 days, after which erythematous [[papules]] arise.
*Approximately 2 to 3 days after symptom onset, papules evolve into [[Boil|pustules]].<ref name="Spinola2002">{{cite journal|last1=Spinola|first1=S. M.|title=Immunopathogenesis of Haemophilus ducreyi Infection (Chancroid)|journal=Infection and Immunity|volume=70|issue=4|year=2002|pages=1667–1676|issn=00199567|doi=10.1128/IAI.70.4.1667-1676.2002}}</ref>
*Pustules may resolve spontaneously or ulcerate in approximately 1-2 weeks since formation. Patients typically develop between 1 to 4 [[ulcers]].
*[[Inguinal]] [[lymphadenitis]] develops in approximately half of patients, usually unilaterally and more commonly in males than females, 1 to 2 weeks after appearance of primary ulcer.<ref name="Lewis2003">{{cite journal|last1=Lewis|first1=D A|title=Chancroid: clinical manifestations, diagnosis, and management|journal=Sexually Transmitted Infections|volume=79|issue=1|year=2003|pages=68–71|issn=13684973|doi=10.1136/sti.79.1.68}}</ref>
*In approximately 25% of patients with lymphadenitis, lymph nodes may swell to form fluctuant [[Bubo|buboes]]. Untreated buboes may rupture, discharge exudate, and ulcerate.<ref name="Lewis2003" />
 
==Complications==
*[[Superinfection]] of lesions by other anaerobic bacteria such as [[Fusobacterium]] and [[Bacteroides]]<ref name="cur">{{cite book|title=CURRENT Diagnosis & Treatment of Sexually Transmitted Diseases|year=2007|publisher=McGraw-Hill Companies,Inc.|isbn=9780071509619|pages=69–74}}</ref><ref name="ChancroidWikipedia">Chancroid. Wikipedia (July 16, 2015). https://en.wikipedia.org/wiki/Chancroid Accessed January 15, 2016.</ref>
*[[Phimosis]] in men<ref name="Lewis2003" />
*Extensive [[adenitis]] in the absence of treatment
*Development of inguinal [[abscesses]] which may rupture to form a draining [[Sinus (anatomy)|sinus]] or giant ulcer
*Nonhealing ulcers
 
==Prognosis==
*Chancroid is not lethal.
*Prognosis is poor without treatment. Indications of poor prognosis include:
::Nonhealing ulcers
::[[Lymphadenopathy]], especially with the formation and/or rupture of [[Bubo|buboes]]
::[[Superinfection]] of lesions (phagedenic chancroid)


==References==
==References==
{{Reflist|2}}
{{Reflist|2}}


[[Category:Needs content]]
[[Category:Disease]]
[[Category:Sexually transmitted diseases]]
[[Category:Bacterial diseases]]
[[Category:Bacterial diseases]]
[[Category:Infectious disease]]
[[Category:Proteobacteria]]
[[Category:Disease]]


{{WikiDoc Help Menu}}
{{WikiDoc Help Menu}}
{{WikiDoc Sources}}
{{WikiDoc Sources}}

Latest revision as of 17:21, 18 September 2017

Chancroid Microchapters

Home

Patient Information

Overview

Historical Perspective

Pathophysiology

Causes

Classification

Differentiating Chancroid from other Diseases

Epidemiology and Demographics

Risk Factors

Natural History, Complications and Prognosis

Diagnosis

History and Symptoms

Physical Examination

Laboratory Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Chancroid natural history, complications and prognosis On the Web

Most recent articles

Most cited articles

Review articles

Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Chancroid natural history, complications and prognosis

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA onChancroid natural history, complications and prognosis

CDC onChancroid natural history, complications and prognosis

Chancroid natural history, complications and prognosisin the news

Blogs onChancroid natural history, complications and prognosis

Directions to Hospitals Treating chancroid

calculators and risk factors for Chancroid natural history, complications and prognosis

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Yazan Daaboul, M.D.; Nate Michalak, B.A.; Serge Korjian M.D.

Overview

Chancroid symptoms typically develop 4 to 10 days after infection. Initial indication of infection involves formation of erythematous papules which develop into pustules after several days. Approximately 1-2 weeks after pustule formation, the lesions may ulcerate. Patients typically develop 1 to 4 ulcers. Lymphadenopathy develops in approximately half of patients, predominantly in males, 1 to 2 weeks after appearance of the primary ulcer. In approximately 25% of patients with lymphadenopathy, lymph nodes may swell to form fluctuant buboes which may rupture and form giant ulcers. Prognosis is poor without treatment. Complications from chancroid include: superinfection of lesions, extensive adenitis, development of inguinal abscesses, and nonhealing ulcers.

Natural History

  • The incubation period for H. ducreyi is typically 4 to 10 days, after which erythematous papules arise.
  • Approximately 2 to 3 days after symptom onset, papules evolve into pustules.[1]
  • Pustules may resolve spontaneously or ulcerate in approximately 1-2 weeks since formation. Patients typically develop between 1 to 4 ulcers.
  • Inguinal lymphadenitis develops in approximately half of patients, usually unilaterally and more commonly in males than females, 1 to 2 weeks after appearance of primary ulcer.[2]
  • In approximately 25% of patients with lymphadenitis, lymph nodes may swell to form fluctuant buboes. Untreated buboes may rupture, discharge exudate, and ulcerate.[2]

Complications

Prognosis

  • Chancroid is not lethal.
  • Prognosis is poor without treatment. Indications of poor prognosis include:
Nonhealing ulcers
Lymphadenopathy, especially with the formation and/or rupture of buboes
Superinfection of lesions (phagedenic chancroid)

References

  1. ↑ Spinola, S. M. (2002). "Immunopathogenesis of Haemophilus ducreyi Infection (Chancroid)". Infection and Immunity. 70 (4): 1667–1676. doi:10.1128/IAI.70.4.1667-1676.2002. ISSN 0019-9567.
  2. ↑ 2.0 2.1 2.2 Lewis, D A (2003). "Chancroid: clinical manifestations, diagnosis, and management". Sexually Transmitted Infections. 79 (1): 68–71. doi:10.1136/sti.79.1.68. ISSN 1368-4973.
  3. ↑ CURRENT Diagnosis & Treatment of Sexually Transmitted Diseases. McGraw-Hill Companies,Inc. 2007. pp. 69–74. ISBN 9780071509619.
  4. ↑ Chancroid. Wikipedia (July 16, 2015). https://en.wikipedia.org/wiki/Chancroid Accessed January 15, 2016.


Template:WikiDoc Sources

Retrieved from "https://www.wikidoc.org/index.php?title=Chancroid_natural_history,_complications_and_prognosis&oldid=1354496"