Blue rubber bleb nevus syndrome natural history, complications and prognosis: Difference between revisions
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==Natural History, Complications and Prognosis== | ==Natural History, Complications and Prognosis== | ||
=== Natural History === | |||
* The symptoms of [[blue rubber bleb nevus syndrome]] usually develop in the first decade of life, and start with symptoms such as <ref name="pmid10881076">{{cite journal |vauthors=Rodrigues D, Bourroul ML, Ferrer AP, Monteiro Neto H, Gonçalves ME, Cardoso SR |title=Blue rubber bleb nevus syndrome |journal=Rev Hosp Clin Fac Med Sao Paulo |volume=55 |issue=1 |pages=29–34 |date=2000 |pmid=10881076 |doi= |url=}}</ref> | |||
** Skin spots ([[nevi]]) | |||
** [[Bleeding]] | |||
** Increased [[sweating]] around the areas of [[lesions]] | |||
===Complications=== | ===Complications=== | ||
Common [[complications]] of [[blue rubber bleb nevus syndrome]] include:<ref name="pmid12024162">{{cite journal |author=Dwivedi M, Misra SP |title=Blue rubber bleb nevus syndrome causing upper GI hemorrhage: a novel management approach and review |journal=[[Gastrointestinal Endoscopy]] |volume=55 |issue=7 |pages=943–6 |year=2002 |month=June |pmid=12024162 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0016510702038622 |accessdate=2012-09-10}}</ref><ref name="pmid15097941">{{cite journal |vauthors=Nahm WK, Moise S, Eichenfield LF, Paller AS, Nathanson L, Malicki DM, Friedlander SF |title=Venous malformations in blue rubber bleb nevus syndrome: variable onset of presentation |journal=J. Am. Acad. Dermatol. |volume=50 |issue=5 Suppl |pages=S101–6 |date=May 2004 |pmid=15097941 |doi=10.1016/S0190 |url=}}</ref><ref name="pmid25493043">{{cite journal |vauthors=Jin XL, Wang ZH, Xiao XB, Huang LS, Zhao XY |title=Blue rubber bleb nevus syndrome: a case report and literature review |journal=World J. Gastroenterol. |volume=20 |issue=45 |pages=17254–9 |date=December 2014 |pmid=25493043 |doi=10.3748/wjg.v20.i45.17254 |url=}}</ref><ref name="pmid19518008">{{cite journal |vauthors=Feingold RM |title=The blue rubber bleb [corrected] nevus syndrome |journal=J Insur Med |volume=41 |issue=1 |pages=67–71 |date=2009 |pmid=19518008 |doi= |url=}}</ref> | Common [[complications]] of [[blue rubber bleb nevus syndrome]] include:<ref name="pmid12024162">{{cite journal |author=Dwivedi M, Misra SP |title=Blue rubber bleb nevus syndrome causing upper GI hemorrhage: a novel management approach and review |journal=[[Gastrointestinal Endoscopy]] |volume=55 |issue=7 |pages=943–6 |year=2002 |month=June |pmid=12024162 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0016510702038622 |accessdate=2012-09-10}}</ref><ref name="pmid15097941">{{cite journal |vauthors=Nahm WK, Moise S, Eichenfield LF, Paller AS, Nathanson L, Malicki DM, Friedlander SF |title=Venous malformations in blue rubber bleb nevus syndrome: variable onset of presentation |journal=J. Am. Acad. Dermatol. |volume=50 |issue=5 Suppl |pages=S101–6 |date=May 2004 |pmid=15097941 |doi=10.1016/S0190 |url=}}</ref><ref name="pmid25493043">{{cite journal |vauthors=Jin XL, Wang ZH, Xiao XB, Huang LS, Zhao XY |title=Blue rubber bleb nevus syndrome: a case report and literature review |journal=World J. Gastroenterol. |volume=20 |issue=45 |pages=17254–9 |date=December 2014 |pmid=25493043 |doi=10.3748/wjg.v20.i45.17254 |url=}}</ref><ref name="pmid19518008">{{cite journal |vauthors=Feingold RM |title=The blue rubber bleb [corrected] nevus syndrome |journal=J Insur Med |volume=41 |issue=1 |pages=67–71 |date=2009 |pmid=19518008 |doi= |url=}}</ref> |
Revision as of 17:46, 11 December 2018
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Common complications of blue rubber bleb nevus syndrome include GI bleeding, Intussusception, and Intestinal perforation.
Natural History, Complications and Prognosis
Natural History
- The symptoms of blue rubber bleb nevus syndrome usually develop in the first decade of life, and start with symptoms such as [1]
Complications
Common complications of blue rubber bleb nevus syndrome include:[2][3][4][5]
- Acute GI bleeding[6]
- Anemia due to bleeding[7]
- Intussusception
- Bowel infarction
- Intestinal torsion
- Necrosis of intestinal mucosa
- Intestinal perforation
- Volvulus
- Stroke
- Abscess formation and
- Even death due to central nervous system involvement.
Prognosis
- Depending on the extent of the blue rubber bleb nevus syndrome at the time of diagnosis, the prognosis may vary.
- Prognosis of the blue rubber bleb nevus syndrome is depend on the following:
- Severity of the signs and symptoms at the time of diagnosis
- Vascular malformations size and number
- Vascular malformations locations
- Overall, prognosis is good and patients with blue rubber bleb nevus syndrome have normal lifespan if it diagnosed intime.
References
- ↑ Rodrigues D, Bourroul ML, Ferrer AP, Monteiro Neto H, Gonçalves ME, Cardoso SR (2000). "Blue rubber bleb nevus syndrome". Rev Hosp Clin Fac Med Sao Paulo. 55 (1): 29–34. PMID 10881076.
- ↑ Dwivedi M, Misra SP (2002). "Blue rubber bleb nevus syndrome causing upper GI hemorrhage: a novel management approach and review". Gastrointestinal Endoscopy. 55 (7): 943–6. PMID 12024162. Retrieved 2012-09-10. Unknown parameter
|month=
ignored (help) - ↑ Nahm WK, Moise S, Eichenfield LF, Paller AS, Nathanson L, Malicki DM, Friedlander SF (May 2004). "Venous malformations in blue rubber bleb nevus syndrome: variable onset of presentation". J. Am. Acad. Dermatol. 50 (5 Suppl): S101–6. doi:10.1016/S0190. PMID 15097941.
- ↑ Jin XL, Wang ZH, Xiao XB, Huang LS, Zhao XY (December 2014). "Blue rubber bleb nevus syndrome: a case report and literature review". World J. Gastroenterol. 20 (45): 17254–9. doi:10.3748/wjg.v20.i45.17254. PMID 25493043.
- ↑ Feingold RM (2009). "The blue rubber bleb [corrected] nevus syndrome". J Insur Med. 41 (1): 67–71. PMID 19518008.
- ↑ Dobru D, Seuchea N, Dorin M, Careianu V (September 2004). "Blue rubber bleb nevus syndrome: case report and literature review". Rom J Gastroenterol. 13 (3): 237–40. PMID 15470538.
- ↑ Lybecker MB, Stawowy M, Clausen N (December 2016). "Blue rubber bleb naevus syndrome: a rare cause of chronic occult blood loss and iron deficiency anaemia". BMJ Case Rep. 2016. doi:10.1136/bcr-2016-216963. PMID 27999128.