Adiposogenital dystrophy: Difference between revisions

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'''For patient information, click [[Adiposogenital dystrophy (patient information)|here]]'''
'''For patient information, click [[Adiposogenital dystrophy (patient information)|here]]'''
{{CMG}} [[Ogechukwu Hannah Nnabude, MD]]
{{Adiposogenital_dystrophy}}
{{Adiposogenital_dystrophy}}
{{GS}}


{{SK}}: Froehlich syndrome; frohlich syndrome; hypothalamic infantilism with obesity syndrome.
{{SK}}: Froehlich syndrome; frohlich syndrome; hypothalamic infantilism with obesity syndrome
It has several other names:<ref>[http://www.rarediseases.org/search/rdbdetail_abstract.html?disname=Froelich%27s%20Syndrome National Organisation for Rare Disorders - Froelich's syndrome]</ref>
 
==[[Adiposogenital dystrophy overview|Overview]]==


* ''Babinski-Fröhlich syndrome''<ref>{{WhoNamedIt|synd|1792}} - Babinski-Fröchlich syndrome</ref> (named after [[Joseph Babinski]]<ref>J. F. Babinski. Tumeur du corps pituitaire sans acromégalie et avec arrêt de développement des organes génitaux. Revue neurologique, Paris, 1900, 8: 531-535. </ref> and [[Alfred Fröhlich]],<ref>A. Fröhlich. Ein Fall von Tumor der Hypophysis cerebri ohne Akromegalie. Wiener klinische Rundschau, 1901, 15: 833-836; 906-908. </ref> but probably first described by [[Giovanni Battista Morgagni|Morgagni]]). (It was given its name by [[Harvey Cushing]].)<ref name="pmid17969845">{{cite journal |author=Zárate A, Saucedo R |title=[The adiposogenital distrophy or Frohlich syndrome and the beginning of the concept of neuroendocrinology] |language=Spanish; Castilian |journal=Gac Med Mex |volume=143 |issue=4 |pages=349–50 |year=2007 |pmid=17969845 |doi=}}</ref>
==[[Adiposogenital dystrophy historical perspective|Historical Perspective]]==
* ''Froelich's syndrome''
* ''Frölich's Syndrome''
* ''Hypothalamic Infantilism-Obesity''
* ''Launois-Cleret Syndrome''
* ''Sexual Infantilism''


==[[Adiposogenital dystrophy classification|Classification]]==


==Presentation==
==[[Adiposogenital dystrophy pathophysiology|Pathophysiology]]==
It is characterized by:
* Feminine [[obesity]]
* [[Growth retardation]] and retarded [[sexual development]], [[atrophy]] or [[hypoplasia]] of the [[gonads]], and altered [[secondary sex characteristics]],
* [[headaches]]
* [[mental retardation]], problems with [[Visual perception|vision]]
* [[polyuria]], [[polydipsia]].


It is usually associated with [[tumor|tumours]] of the [[hypothalamus]], causing increased [[appetite]] and depressed [[secretion]] of [[gonadotropin]]. It seems to affect [[males]] mostly.
==[[Adiposogenital dystrophy causes|Causes]]==


Many overweight children may appear to have the disorder because of the concurrence of obesity and retarded sexual development; these children have no [[endocrine]] disturbances, however, and they mature normally after delayed [[puberty]].
==[[Adiposogenital dystrophy differential diagnosis|Differentiating Adiposogenital dystrophy from other Diseases]]==


==Synonyms==
==[[Adiposogenital dystrophy epidemiology and demographics|Epidemiology and Demographics]]==


==[[Adiposogenital dystrophy risk factors|Risk Factors]]==


==See also==
==[[Adiposogenital dystrophy screening|Screening]]==
* [[Prader-Willi syndrome]], to which it might resemble. However, this is a [[genetic disorder]].


==References==
==[[Adiposogenital dystrophy natural history, complications and prognosis|Natural History, Complications and Prognosis]]==
{{reflist|2}}
 
==Diagnosis==
[[Adiposogenital dystrophy history and symptoms|History and Symptoms]] | [[Adiposogenital dystrophy physical examination|Physical Examination]] | [[Adiposogenital dystrophy laboratory findings|Laboratory Findings]] | [[Adiposogenital dystrophy electrocardiogram|Electrocardiogram]] | [[Adiposogenital dystrophy head x ray|Head X Ray]] | [[Adiposogenital dystrophy CT|CT]] | [[Adiposogenital dystrophy MRI|MRI]] | [[Adiposogenital dystrophy vision_test|Vision Test]] | [[Adiposogenital dystrophy other imaging findings|Other Imaging Findings]] | [[Adiposogenital dystrophy other diagnostic studies|Other Diagnostic Studies]]
 
==Treatment==
[[Adiposogenital dystrophy medical therapy|Medical Therapy]] | [[Adiposogenital dystrophy primary prevention|Primary Prevention]] | [[Adiposogenital dystrophy secondary prevention|Secondary Prevention]] | [[Adiposogenital dystrophy cost-effectiveness of therapy|Cost-Effectiveness of Therapy]] |  [[Adiposogenital dystrophy future or investigational therapies|Future or Investigational Therapies]]
 
==Case Studies==
 
[[Adiposogenital dystrophy case study one|Case #1]]
 
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[[de:Fröhlich-Syndrom]]
[[de:Fröhlich-Syndrom]]
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Latest revision as of 03:57, 18 August 2021

Adiposogenital dystrophy
ICD-10 E23.6
ICD-9 253.8
DiseasesDB 29318

For patient information, click here

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Ogechukwu Hannah Nnabude, MD

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Synonyms and keywords:: Froehlich syndrome; frohlich syndrome; hypothalamic infantilism with obesity syndrome

Overview

Historical Perspective

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Pathophysiology

Causes

Differentiating Adiposogenital dystrophy from other Diseases

Epidemiology and Demographics

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Diagnosis

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