Riedel's thyroiditis
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| Riedel's thyroiditis Classification and external resources | |
| ICD-10 | E06.5 |
|---|---|
| ICD-9 | 245.3 |
| DiseasesDB | 11590 |
| eMedicine | med/2036 |
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Riedel's thyroiditis, also called Riedel's struma is a chronic form of thyroiditis.
Pathophysiology
Riedel's thyroiditis is characterized by a replacement of the normal thyroid parenchyma by a dense fibrosis that invades adjacent structures of the neck and extends beyond the thyroid capsule.[1] This makes the thyroid gland stone-hard and fixed to adjacent structures.
A shared mechanism with retroperitoneal fibrosis and sclerosing cholangitis has been suggested.[2]
Prevalence
Riedel's thyroiditis is classified as rare. Most patients remain euthyroid, but approximately 30% of patients become hypothyroid and very few patients are hyperthyroid. It is most seen in women.[3]
Treatment
Tamoxifen has been proposed as part of a treatment plan.[4]
Eponym
It is named for Bernhard Riedel. He first recognized the disease In 1883 and published its description in 1896.[5][6]
References
- ↑ Cho MH, Kim CS, Park JS, et al (August 2007). "Riedel's thyroiditis in a patient with recurrent subacute thyroiditis: a case report and review of the literature". Endocr. J. 54 (4): 559–62. PMID 17603227.
- ↑ De Boer WA (May 1993). "Riedel's thyroiditis, retroperitoneal fibrosis, and sclerosing cholangitis: diseases with one pathogenesis?". Gut 34 (5): 714. PMID 8504980.
- ↑ eMedicine
- ↑ Dabelic N, Jukic T, Labar Z, Novosel SA, Matesa N, Kusic Z (April 2003). "Riedel's thyroiditis treated with tamoxifen" (PDF). Croat. Med. J. 44 (2): 239–41. PMID 12698518.
- ↑ B. M. C. L. Riedel. Die chronische, zur Bildung eisenharter Tumoren führende Entzündung der Schilddrüse. Verhandlungen der deutschen Gesellschaft für Chirurgie, 1896, 25: 101-105.
- ↑ synd/3242 at Who Named It
de:Riedel-Struma
it:Tiroidite di Riedel
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
