Grainy head transcription factor gene transcriptions: Difference between revisions

Associate Editor(s)-in-Chief: Henry A. Hoff

"The defined GRHL1 DNA‐binding consensus sequence (AACCGGTT) was identical to that defined for GRHL3, and also matched the consensus sequence for Drosophila GRH DNA binding, which we had previously identified by alignment of multiple GRH‐responsive gene regulatory regions (Wilanowski et al, 2002; Ting et al, 2005). Of note, the first of the two cytosines and the second of the guanines were invariant in both GRHL1 and GRHL3 CASTing assays."^[1]

Human genes

Interactions

Consensus sequences

"The putative GRHL1‐binding motif (GACTGGTT) is perfectly conserved, together with 6 bp upstream and 12 bp downstream flanking sequences, in three of the Dsg1 promoters: mouse Dsg1α, mouse Dsg1γ, and human DSG1 [...]. In the mouse Dsg1β promoter, this motif is slightly different (AACTGGTT), although the flanking sequences are still conserved."^[1]

All "GRHL proteins bind to the consensus sequence 5′-AACCGGTT-3′ as a dimer [37,38,39]."^[2]

Samplings

Copying the GRHL1 DNA‐binding consensus sequence AACCGGTT and putting it in "⌘F" finds none located between ZSCAN22 and A1BG and none between ZNF497 and A1BG as can be found by the computer programs.

References

↑ ^1.0 ^1.1 Tomasz Wilanowski, Jacinta Caddy, Stephen B Ting, Nikki R Hislop, Loretta Cerruti, Alana Auden, Lin‐Lin Zhao, Stephen Asquith, Sarah Ellis, Rodney Sinclair, John M Cunningham and Stephen M Jane (21 February 2008). "Perturbed desmosomal cadherin expression in grainy head‐like 1‐null mice". The EMBO Journal. 27: 886–897. doi:10.1038/emboj.2008.24. PMID 18288204. Retrieved 7 February 2020.
↑ Felix J. Boivin & Kai M. Schmidt-Ott (15 December 2018). "Functional roles of Grainyhead-like transcription factors in renal development and disease". Pediatric Nephrology. 35: 181–190. doi:10.1007/s00467-018-4171-4. Retrieved 5 January 2021.

External links

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transcriptions Transcription factor 3 gene transcriptions Transcription factory gene transcriptions Transcription start site gene transcriptions Translational control sequence gene transcriptions U box gene transcriptions Unfolded protein response element gene transcriptions Upstream response element gene transcriptions Upstream stimulatory factor gene transcriptions UTR promoter gene transcriptions V and P box gene transcriptions V box gene transcriptions Vhr1p gene transcriptions Vitamin D response element gene transcriptions W box gene transcriptions X box gene transcriptions Xbp1p gene transcriptions X core promoter element gene transcriptions Xenobiotic response element gene transcriptions Xenobiotic responsive element gene transcriptions Yap1p,2p gene transcriptions Y box gene transcriptions YY1 gene transcriptions Zap1p gene transcriptions Z box gene transcriptions Zinc responsive element gene transcriptions

@@ Line 23: / Line 23: @@
 "The putative GRHL1‐binding motif (GACTGGTT) is perfectly conserved, together with 6 bp upstream and 12 bp downstream flanking sequences, in three of the ''Dsg1'' promoters: mouse ''Dsg1α'', mouse ''Dsg1γ'', and human ''DSG1'' [...]. In the mouse Dsg1β promoter, this motif is slightly different (AACTGGTT), although the flanking sequences are still conserved."<ref name=Wilanowski/>
+All "GRHL proteins bind to the consensus sequence 5′-AACCGGTT-3′ as a dimer [37,38,39]."<ref name=Boivin>{{ cite journal
+|author=Felix J. Boivin & Kai M. Schmidt-Ott
+|title=Functional roles of Grainyhead-like transcription factors in renal development and disease
+|journal=Pediatric Nephrology
+|date=15 December 2018
+|volume=35
+|issue=
+|pages=181–190
+|url=https://link.springer.com/article/10.1007/s00467-018-4171-4
+|arxiv=
+|bibcode=
+|doi=10.1007/s00467-018-4171-4
+|pmid=
+|accessdate=5 January 2021 }}</ref>
 ==Samplings==

Grainy head transcription factor gene transcriptions: Difference between revisions

Revision as of 02:02, 6 January 2021

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