Tubular fluid

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Editor-In-Chief: Steven C. Campbell, M.D., Ph.D., Professor of Surgery, Residency Program Director, Section of Urologic Oncology, Glickman Urological and Kidney Institute, Cleveland Clinic. You can email Dr. Campbell by clicking here. Office phone: 216-444-5595.


Overview

Tubular fluid is the fluid in the tubules of the kidney. It starts as a renal ultrafiltrate in the glomerulus, changes composition through the nephron, and ends up as urine leaving through the ureters.

Composition table

The composition of tubular fluid changes throughout the nephron, from the proximal tubule to the collecting duct:

Concentration (mM) of substances in different segments of nephron and collecting duct system
Substance proximal tubule loop of Henle Distal convoluted tubule Collecting duct system
S1 S2 S3 descending limb thin ascending limb thick ascending limb connecting tubule initial collecting tubule cortical collecting ducts medullary collecting ducts
Na+ 142[1] 142[1] 100[1] 70[1] 40[1]

References

  1. 1.0 1.1 1.2 1.3 1.4 Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3.  Page 777

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