Descending limb of loop of Henle

Jump to: navigation, search
Descending limb of loop of Henle
Gray1128.png
Scheme of renal tubule and its vascular supply. (Labeled at center left.)
Nefron.png
Nephron. Diagram is labeled in Polish, but ion flow can still be identified.
Gray's subject #253 1223
Dorlands/Elsevier l_10/12493919

WikiDoc Resources for Descending limb of loop of Henle

Articles

Most recent articles on Descending limb of loop of Henle

Most cited articles on Descending limb of loop of Henle

Review articles on Descending limb of loop of Henle

Articles on Descending limb of loop of Henle in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Descending limb of loop of Henle

Images of Descending limb of loop of Henle

Photos of Descending limb of loop of Henle

Podcasts & MP3s on Descending limb of loop of Henle

Videos on Descending limb of loop of Henle

Evidence Based Medicine

Cochrane Collaboration on Descending limb of loop of Henle

Bandolier on Descending limb of loop of Henle

TRIP on Descending limb of loop of Henle

Clinical Trials

Ongoing Trials on Descending limb of loop of Henle at Clinical Trials.gov

Trial results on Descending limb of loop of Henle

Clinical Trials on Descending limb of loop of Henle at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Descending limb of loop of Henle

NICE Guidance on Descending limb of loop of Henle

NHS PRODIGY Guidance

FDA on Descending limb of loop of Henle

CDC on Descending limb of loop of Henle

Books

Books on Descending limb of loop of Henle

News

Descending limb of loop of Henle in the news

Be alerted to news on Descending limb of loop of Henle

News trends on Descending limb of loop of Henle

Commentary

Blogs on Descending limb of loop of Henle

Definitions

Definitions of Descending limb of loop of Henle

Patient Resources / Community

Patient resources on Descending limb of loop of Henle

Discussion groups on Descending limb of loop of Henle

Patient Handouts on Descending limb of loop of Henle

Directions to Hospitals Treating Descending limb of loop of Henle

Risk calculators and risk factors for Descending limb of loop of Henle

Healthcare Provider Resources

Symptoms of Descending limb of loop of Henle

Causes & Risk Factors for Descending limb of loop of Henle

Diagnostic studies for Descending limb of loop of Henle

Treatment of Descending limb of loop of Henle

Continuing Medical Education (CME)

CME Programs on Descending limb of loop of Henle

International

Descending limb of loop of Henle en Espanol

Descending limb of loop of Henle en Francais

Business

Descending limb of loop of Henle in the Marketplace

Patents on Descending limb of loop of Henle

Experimental / Informatics

List of terms related to Descending limb of loop of Henle


The descending limb of loop of Henle is the portion of the renal tubule constituting the first part of the loop of Henle.

Physiology

The permeability is as follows:

Substance Permeability
ions Low permeability. Sodium and chloride ions do not easily pass through. [1]
urea Moderate permeability.[2]
water Highly permeable. Water is readily reabsorbed from the descending limb by osmosis.[3]

Also, the medullary interstitium is highly concentrated (because of the activity of the ascending limb), leading to a strong osmotic gradient from the descending limb to the medulla.

Because of these factors, the concentration of the urine increases dramatically in the descending limb. Osmolality can reach up to 1400 mOsmol/kg by the end of the descending limb.[3]

Histology

The epithelium is low simple cuboidal.[4]

They can be distinguished from the vasa recta by the absence of blood, and they can be distinguished from the thick ascending limb by the thickness of the epithelium.[5]

Nomenclature

Like the ascending limb, the descending limb has thick and thin portions. However, this distinction is not as important physiologically as in the ascending limb, so often the two are treated as one structure. The thick descending limb is less important than the thin descending limb, so often the terms "descending limb" and "thin descending limb" are used interchangeably.

Some sources simply refer to a "thin limb". In this context, the thin ascending limb of loop of Henle would be included.

Additional images

References

  1. http://clem.mscd.edu/~raoa/bio2320/uriphys/sld019.htm
  2. Physiology at MCG 7/7ch08/7ch08p09
  3. 3.0 3.1 Physiology at MCG 7/7ch07/7ch07p09 Cite error: Invalid <ref> tag; name "gp7ch07p09" defined multiple times with different content
  4. Organology at UC Davis Urinary/mammal/medulla/medulla1 - "Mammal, kidney medulla (LM, Medium)"
  5. Histology at Boston University 15804loa

This article was originally based on an entry from a public domain edition of Gray's Anatomy. As such, some of the information contained herein may be outdated. Please edit the article if this is the case, and feel free to remove this notice when it is no longer relevant.


Linked-in.jpg