Gestational trophoblastic disease
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| Gestational trophoblastic disease Classification and external resources | |
| DiseasesDB | 2602 |
|---|---|
| MedlinePlus | 001496 |
| eMedicine | med/866 |
| MeSH | D031901 |
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Gestational trophoblastic disease, usually referred to as a mole, is a very rare abnormality of pregnancy in the reproductive female that involves abnormal trophoblast proliferation.
It is the result of a (purely chance) genetic error during the fertilization process that in turn causes the growth of abnormal tissue (which is not an embryo) within the uterus. The growth of this material is disproportionately rapid when compared to normal fetal growth.
Types
There are profound differences in pathological morphology and clinical behavior in various forms of GTD. Types include:
- abnormal placenta, mostly due to abnormal fertilization
- hydatidiform mole (HM)
- frank malignant tumors of trophoblast
- invasive mole, choriocarcinoma (CCA)
- placental site trophoblastic tumor (PSTT)
- epithelioid trophoblastic tumor (ETT)
- not true neoplasms, representing abnormally formed placentas
- exaggerated placenta site (EPS)
- placental site nodule (PSN)
External links
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
