Toxic multinodular goiter
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Overview
Toxic multinodular goitre (also known as toxic nodular goitre, toxic nodular struma) is a form of hyperthyroidism - where there is excess production of thyroid hormones.
It is the second most common cause of hyperthyroidism after Graves disease.
Symptoms
Symptoms of toxic multinodular goitre are similar to that of hyperthyroidism, including:
- heat intolerance
- hyperkinesis
- tremor
- irritability
- weight loss
- increased appetite
- goitre (swelling of the thyroid gland)
- tachycardia (high heart rate - above 180 bpm at rest)
Related eponym
Plummer's disease is named after an American physician Henry Stanley Plummer but refers to a single toxic nodule (adenoma) which may present with the background of a suppressed multinodular goitre.[1]
Footnotes
External links
Acknowledgements
The content on this page was first contributed by: C. Michael Gibson, M.S., M.D.
Initial content for this page in some instances came from Wikipedia
List of contributors:
Suggested Reading and Key General References
Suggested Links and Web Resources
For Patients
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .

