Tiopronin
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| Image:Tiopronin.svg | |
| Tiopronin
| |
| Systematic (IUPAC) name | |
| [(2-mercaptopropanoyl)amino]acetic acid | |
| Identifiers | |
| CAS number | |
| ATC code | R05 |
| PubChem | |
| Chemical data | |
| Formula | C5H9NO3S |
| Mol. mass | 163.196 g/mol |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
C(US) |
| Legal status | |
| Routes | ? |
Tiopronin (trade name Thiola) is a prescription thiol drug used to control the rate of cystine solidification and excretion in the disease cystinuria. It is a white crystalline powder. Due to its rarity, it falls under the classification of "orphan drug".
Side effects
Tiopronin may present a wide variety of side effects, but side effects are usually limited and subside over time with continued usage. With the rarity of the disease, tiopronin has not been studied substantially, with an extremely low percentage of individuals available for testing.
Other uses
Tiopronin is used primarily for cystinuria and is well known in the cystinuric community. It may also be used for Wilson's disease (an overload of copper in the body), and certain types of rare arthritis. It should be mentioned though, that tiopronin is not an anti-inflammatory.
Depending on the severity of a person's cystinuria, tiopronin may be taken for life, possibly starting in early childhood.
See also
References
Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
