Tenase

You don't need to be Editor-In-Chief to add or edit content to WikiDoc. You can begin to add to or edit text on this WikiDoc page by clicking on the edit button at the top of this page. Next enter or edit the information that you would like to appear here. Once you are done editing, scroll down and click the Save page button at the bottom of the page.

WikiDoc Resources for Tenase
Articles
Most recent articles on Tenase Most cited articles on Tenase Review articles on Tenase Articles on Tenase in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Tenase Images of Tenase Photos of Tenase Podcasts & MP3s on Tenase Videos on Tenase
Evidence Based Medicine
Cochrane Collaboration on Tenase Bandolier on Tenase TRIP on Tenase
Clinical Trials
Ongoing Trials on Tenase at Clinical Trials.gov Trial results on Tenase Clinical Trials on Tenase at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Tenase NICE Guidance on Tenase NHS PRODIGY Guidance FDA on Tenase CDC on Tenase
Books
Books on Tenase
News
Tenase in the news Be alerted to news on Tenase News trends on Tenase
Commentary
Blogs on Tenase
Definitions
Definitions of Tenase
Patient Resources / Community
Patient resources on Tenase Discussion groups on Tenase Patient Handouts on Tenase Directions to Hospitals Treating Tenase Risk calculators and risk factors for Tenase
Healthcare Provider Resources
Symptoms of Tenase Causes & Risk Factors for Tenase Diagnostic studies for Tenase Treatment of Tenase
Continuing Medical Education (CME)
CME Programs on Tenase
International
Tenase en Espanol Tenase en Francais
Businness
Tenase in the Marketplace Patents on Tenase
Experimental / Informatics
List of terms related to Tenase

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Phone:617-525-6884

Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

The tenase complex is formed by the activated forms of the blood coagulation factors factor VIII and factor IX. It forms on a phospholipid surface in the presence of calcium and is responsible for the activation of factor X.

v • d • e Pathology: hematology, myeloid hematologic disease (primarily D50-D77, 280-289)
RBCs/ hemoglobinopathy	+ Polycythemia - Macrocytosis - Anemia Nutritional Iron deficiency anemia (Plummer-Vinson syndrome), Megaloblastic anemia (Pernicious anemia) Hemolytic Hereditary enzyme: G6PD Deficiency - Pyruvate kinase deficiency - Triosephosphate isomerase deficiency hemoglobin: Thalassemia - Sickle-cell disease/trait membrane: Hereditary spherocytosis - Hereditary elliptocytosis - Hereditary stomatocytosis Acquired Autoimmune (Warm, Cold), HUS, MAHA, PNH, PCH, Myelophthisic Aplastic Acquired PRCA, Diamond-Blackfan anemia, Fanconi anemia, Sideroblastic anemia Blood tests Normocytic - Microcytic - Macrocytic - Normochromic - Hypochromic Other Methemoglobinemia
Coagulation/platelets/ coagulopathy/ bleeding diathesis	+ Hypercoagulability primary: Antithrombin III deficiency - Protein C deficiency/Activated protein C resistance/Protein S deficiency/Factor V Leiden - Hyperprothrombinemia acquired: DIC (Congenital afibrinogenemia, Purpura fulminans) - autoimmune (Antiphospholipid) Other Essential thrombocytosis - clotting factor: Hemophilia (A/VIII, B/IX, C/XI) • Von Willebrand disease • Hypoprothrombinemia/II - XIII platelet function: Bernard-Soulier syndrome - Glanzmann's thrombasthenia - Gray platelet syndrome - May Hegglin anomaly - Pelger-Huet anomaly Purpura: Henoch-Schönlein, ITP (Evans syndrome), TTP Thrombocytopenia (Heparin-induced thrombocytopenia)
Monocytes/ macrophages	+ Histiocytosis WHO-I (Langerhans cell histiocytosis) WHO-II/non-Langerhans-cell (Juvenile xanthogranuloma, Hemophagocytic lymphohistiocytosis) WHO-III/malignant (Acute monocytic leukemia, Malignant histiocytosis, Erdheim-Chester disease) Other Chronic granulomatous disease -cytosis: Monocytosis - -penia: Monocytopenia
Granulocytes	+ -cytosis: granulocytosis (Neutrophilia, Eosinophilia, Basophilia) - -penia: Granulocytopenia/agranulocytosis (Neutropenia/Kostmann syndrome, Eosinopenia, Basopenia)
See also hematological malignancy and immune disorders

v • d • e Proteins: coagulation
Coagulation factors	intrinsic pathway (FXII, FXI, FIX, FVIII) - extrinsic pathway (Tissue factor, FVII) - common pathway (FX, FV, (Pro)thrombin / FII, Fibrin / FI, FXIII) - HMWK - vWF - Kallikrein
Inhibitors	Antithrombin - Protein C - Protein S - Protein Z - ZPI - TFPI
Fibrinolysis	Plasmin - tPA/urokinase - PAI-1/2 - α2-AP - α2-macroglobulin - TAFI

v • d • e WikiDoc Research Resources for Tenase
Articles on Tenase	Most recent articles on Tenase • Most cited articles on Tenase • Review articles on Tenase • Articles on Tenase in N Eng J Med, Lancet, BMJ
Media (Slides, Video, Images, MP3) on Tenase	Powerpoint slides on Tenase • Images of Tenase • Photos of Tenase • Podcasts & MP3s on Tenase • Videos on Tenase
Evidence Based Medicine Regarding Tenase	Cochrane Collaboration on Tenase • Bandolier on Tenase • TRIP on Tenase
Cost Effectiveness of Tenase	Cost Effectiveness of Tenase
Clinical Trials Involving Tenase	Ongoing Trials on Tenase at Clinical Trials.gov • Trial results on Tenase • Clinical Trials on Tenase at Google
Guidelines / Policies / Government Resources (FDA/CDC) Regarding Tenase	US National Guidelines Clearinghouse on Tenase • NICE Guidance on Tenase • NHS PRODIGY Guidance • FDA on Tenase • CDC on Tenase
Textbook Information on Tenase	Books and Textbook Information on Tenase
Pharmacology Resources on Tenase	Dosing of Tenase • Drug interactions with Tenase • Side effects of Tenase • Allergic reactions to Tenase • Overdose information on Tenase • Carcinogenicity information on Tenase • Tenase in pregnancy • Pharmacokinetics of Tenase •
Genetics, Pharmacogenomics, and Proteinomics of Tenase	Genetics of Tenase • Pharmacogenomics of Tenase • Proteomics of Tenase
Newstories on Tenase	Tenase in the news • Be alerted to news on Tenase • News trends on Tenase
Commentary on Tenase	Blogs on Tenase
Patient Resources on Tenase	Patient resources on Tenase • Discussion groups on Tenase • Patient Handouts on Tenase • Directions to Hospitals Treating Tenase • Risk calculators and risk factors for Tenase
Healthcare Provider Resources on Tenase	Symptoms of Tenase • Causes & Risk Factors for Tenase • Diagnostic studies for Tenase • Treatment of Tenase
Continuing Medical Education (CME) Programs on Tenase	CME Programs on Tenase
International Resources on Tenase	Tenase en Espanol • Tenase en Francais
Business Resources on Tenase	Tenase in the Marketplace • Patents on Tenase
Informatics Resources on Tenase	List of terms related to Tenase

WikiDoc Help Menu Quick Start.. Get Started Here! How to Login How to Search Pages How to Start a New Page How to Edit a Page Cheat Sheet Editing basics Learning Basic Formatting How to make Links in WikiDoc & to External Sites How to Make Lists How to Ignoring Formatting Adding References or Footnotes to Articles Tracking Changes You Have Made How to Put an Article Into a Category When Multiple Topics Should Go To The Same Page (MI, Acute MI, AMI) Using Redirection Advanced editing How to Make Tables How to Insert Images and Other Media How to Add Video Help:How to Make Columns Web Colors How To Make Templates How to Move Pages Inserting Dynamic Dates and Times Inserting WikiDoc Statistics Editing the Table of Contents Communicating your edits Let others know what you changed: The importance of Edit Summaries Minor Edits Edit Conflicts Help Videos You Can Watch Getting Started Video

Acknowledgement and Attribution Regarding Sources of Content

Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .