Primary biliary cirrhosis historical perspective

Jump to navigation Jump to search

Primary Biliary Cirrhosis Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Primary Biliary Cirrhosis from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Primary biliary cirrhosis historical perspective On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Primary biliary cirrhosis historical perspective

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Primary biliary cirrhosis historical perspective

CDC on Primary biliary cirrhosis historical perspective

Primary biliary cirrhosis historical perspective in the news

Blogs on Primary biliary cirrhosis historical perspective

Directions to Hospitals Treating Primary biliary cirrhosis

Risk calculators and risk factors for Primary biliary cirrhosis historical perspective

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aysha Anwar, M.B.B.S[2], Anmol Pitliya, M.B.B.S. M.D.[3]

Overview

In 1851, Addison and Gull first described the clinical picture of progressive obstructive jaundice in the absence of mechanical obstruction of the large bile ducts. Ahrens et al in 1950, coined the term primary biliary cirrhosis for this disease. In 1986, the association between primary biliary cirrhosis and anti-mitochondrial antibodies was first reported.

Historical Perspective

Discovery

  • In 1851, Addison and Gull first described primary biliary cirrhosis in the Guys hospital report titled as "On a Certain Affectation of the Skin Vitiligoiidea-alpha plana, beta tuberosa".[1]
  • In 1950, Ahrens et al. coined the term "primary biliary cirrhosis.[2]
  • In 1956, Walker et al first described the association between anti-mitochondrial antibodies and primary biliary cirrhosis.[3]
  • In 1986, the association between primary biliary cirrhosis and anti-mitochondrial antibodies was first reported.[4]

References

  1. Cheung AC, Montano-Loza A, Swain M, Vincent C, Renner E, Sherman M; et al. (2015). "Time to make the change from 'primary biliary cirrhosis' to 'primary biliary cholangitis'". Can J Gastroenterol Hepatol. 29 (6): 293. PMC 4578449. PMID 26196152.
  2. AHRENS EH, PAYNE MA, KUNKEL HG, EISENMENGER WJ, BLONDHEIM SH (1950). "Primary biliary cirrhosis". Medicine (Baltimore). 29 (4): 299–364. PMID 14796348.
  3. WALKER JG, DONIACH D, ROITT IM, SHERLOCK S (1965). "SEROLOGICAL TESTS IN DIAGNOSIS OF PRIMARY BILIARY CIRRHOSIS". Lancet. 1 (7390): 827–31. PMID 14263538.
  4. Mitchison HC, Bassendine MF, Hendrick A; et al. (1986). "Positive antimitochondrial antibody but normal alkaline phosphatase: is this primary biliary cirrhosis?". Hepatology. 6 (6): 1279–84. doi:10.1002/hep.1840060609. PMID 3793004.

Template:WH Template:WS