Pott's disease other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aravind Kuchkuntla, M.B.B.S[2]

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Other diagnostic studies include nucleic acid amplification and demonstration of the acid fast bacilli from the biopsy specimen.

Other Diagnostic Tests

Acid Fast Staining

Demonstration of acid fast bacilli in the CT guided biopsy specimen sample confirms the diagnosis.[1]

Nucleic Acid Amplification Tests (NAAT)

Polymerase chain reaction (PCR) can be used to detect mycobacterial nucleic acid in the biopsy specimen.[2][3]


  1. Kang M, Gupta S, Khandelwal N, Shankar S, Gulati M, Suri S (1999). "CT-guided fine-needle aspiration biopsy of spinal lesions". Acta Radiol. 40 (5): 474–8. PMID 10485234.
  2. Sharma K, Meena RK, Aggarwal A, Chhabra R (2017). "Multiplex PCR as a novel method in the diagnosis of spinal tuberculosis-a pilot study". Acta Neurochir (Wien). 159 (3): 503–507. doi:10.1007/s00701-016-3065-0. PMID 28110400.
  3. Brisson-Noel A, Aznar C, Chureau C, Nguyen S, Pierre C, Bartoli M; et al. (1991). "Diagnosis of tuberculosis by DNA amplification in clinical practice evaluation". Lancet. 338 (8763): 364–6. PMID 1677709.