Plasmodium yoelii
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Plasmodium achiotense is a parasite of the genus Plasmodium subgenus Vinckeia.
Like all Plasmodium species P. yoelii has both vertebrate and insect hosts. The vertebrate hosts for this parasite are mammals.
| Plasmodium yoelii | ||||||||||||||
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| Plasmodium yoelii |
Contents |
Description
This species was described in 1968 by Landau, Michel and Adam.
Geographical occurrence
Clinical features and host pathology
This is a species that infects rodents.
Notes
Its most notable feature is that it is used in the laboratory to infect mice, as a model of human malaria, particularly with respect to the immune response.
It is advantageous to have a whole-animal model of malaria because often it is difficult to know which factors to study in vitro, particularly in a complex system like the immune system. Moreover, for many experiments it is not ethical or practical to use humans.
One of the special things about this particular model is that is has two strains with vastly different pathogenicity. These are generally referred to as the "lethal" and "non-lethal" strains of the species. Comparison of these two strains can be used to deduce which factors may contribute to more serious malaria infections in humans.
References
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
