Oral cancer history and symptoms

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sargun Singh Walia M.B.B.S.[2]; Grammar Reviewer: Natalie Harpenau, B.S.[3]

Overview

A positive history of tobacco chewing or smoking, excessive alcohol intake, poor oral hygiene, metallic dentures, betel liquid use, diet rich in meats and HPV infection in sexual partner is suggestive of oral cancer. The most common symptoms of oral cancer include a sore, irritated lump or thick patch in the mouth, lip, or throat; a white or red patch in the mouth; persistent mouth pain; a lump in the neck; loose tooth; bleeding in the mouth; pain in one ear without hearing loss; weight loss, etc.

History and Symptoms

History

Patients with oral cancer may have a positive history of:
- Tobacco chewing
- Excessive alcohol intake^[1]
- Poor oral hygiene
- Metallic denture use^[2]
- Betel liquid use^[3]
- Diet low in fruits and vegetables and high in consumption of meats
- HPV infection in sexual partner^[4]

Symptoms

Common symptoms of oral cancer include:
- A sore, irritated lump or thick patch in the mouth, lip, or throat
- A white or red patch in the mouth
- Persistent mouth pain
- A lump in the neck
- Loose tooth
- Bleeding in the mouth
- Pain in one ear without hearing loss
- Swelling of jaw that causes dentures to fit poorly or become uncomfortable
- Persistent bad breath
- Numbness in tongue or other areas of the mouth
- Difficulty chewing or swallowing
- Difficulty moving the jaw or tongue
- Weight loss
- A feeling that something is caught in your throat

References

↑ Stornetta A, Guidolin V, Balbo S (2018). "Alcohol-Derived Acetaldehyde Exposure in the Oral Cavity". Cancers (Basel). 10 (1). doi:10.3390/cancers10010020. PMID 29342885.
↑ Rosenquist K, Wennerberg J, Schildt EB, Bladström A, Göran Hansson B, Andersson G (2005). "Oral status, oral infections and some lifestyle factors as risk factors for oral and oropharyngeal squamous cell carcinoma. A population-based case-control study in southern Sweden". Acta Otolaryngol. 125 (12): 1327–36. doi:10.1080/00016480510012273. PMID 16303683.
↑ Su CC, Yang HF, Huang SJ, Lian I (2007). "Distinctive features of oral cancer in Changhua County: high incidence, buccal mucosa preponderance, and a close relation to betel quid chewing habit". J. Formos. Med. Assoc. 106 (3): 225–33. PMID 17389167. Vancouver style error: initials (help)
↑ Shah A, Malik A, Garg A, Mair M, Nair S, Chaturvedi P (2017). "Oral sex and human papilloma virus-related head and neck squamous cell cancer: a review of the literature". Postgrad Med J. 93 (1105): 704–709. doi:10.1136/postgradmedj-2016-134603. PMID 28778951.

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[pmid29342885-1] Stornetta A, Guidolin V, Balbo S (2018). "Alcohol-Derived Acetaldehyde Exposure in the Oral Cavity". Cancers (Basel). 10 (1). doi:10.3390/cancers10010020. PMID 29342885.

[pmid16303683-2] Rosenquist K, Wennerberg J, Schildt EB, Bladström A, Göran Hansson B, Andersson G (2005). "Oral status, oral infections and some lifestyle factors as risk factors for oral and oropharyngeal squamous cell carcinoma. A population-based case-control study in southern Sweden". Acta Otolaryngol. 125 (12): 1327–36. doi:10.1080/00016480510012273. PMID 16303683.

[pmid17389167-3] Su CC, Yang HF, Huang SJ, Lian I (2007). "Distinctive features of oral cancer in Changhua County: high incidence, buccal mucosa preponderance, and a close relation to betel quid chewing habit". J. Formos. Med. Assoc. 106 (3): 225–33. PMID 17389167. Vancouver style error: initials (help)

[pmid28778951-4] Shah A, Malik A, Garg A, Mair M, Nair S, Chaturvedi P (2017). "Oral sex and human papilloma virus-related head and neck squamous cell cancer: a review of the literature". Postgrad Med J. 93 (1105): 704–709. doi:10.1136/postgradmedj-2016-134603. PMID 28778951.

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