Non-Hodgkin lymphoma physical examination
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Preeti Singh, M.B.B.S.[2]
Overview
Common physical examination findings of non-Hodgkin lymphoma include fever, pruritus, petechiae, chest tenderness, abdominal tenderness, hepatomegaly, splenomegaly, peripheral lymphadenopathy, seizures, and central lymphadenopathy.
Physical Examination
Physical examination of patients with Non Hodgkin Lymphoma is usually remarkable for fever, pruritus, petechiae, chest tenderness, abdominal tenderness, hepatomegaly, splenomegaly and peripheral lymphadenopathy.[1][2][3]
Appearance of the Patient
- Patients with Non Hodgkin Lymphoma usually appear cachectic
- Pemberton's sign: development of suffusion, plethora, or duskiness upon elevation of the arms above the head in patients with superior vena cava (SVC) syndrome.
Vital Signs
- Low to high-grade fever
- Tachypnea
- Kussmal respirations may be present in advanced SVCS.
- Asymmetric pulse
Skin
- Skin examination of patients with Non Hodgkin Lymphoma include:
HEENT
- Abnormalities of the head/hair may include:
- Icteric sclera
- Nystagmus
- Patient with superior vena cava syndrome present with:
- Facial tenderness
- Swelling of the face
- Facial flushing/redness face or cheeks
- Drooping eyelid
- Swelling around the eye
- Swelling of the whites of the eyes
Neck
- Cervical lymphadenopathy may be present
- Jugular venous distension
- Hepatojugular reflux
Lungs
- Thoracic masses suggestive of central lymphadenopathy
- Chest tenderness
- Pleural effusion may be present and manifestations may include:
- Lungs are hyporesonant
- Decreased breath sounds
- Asymmetric chest expansion
- Wheezing
Heart
- Cardiovascular examination of patients with Non Hodgkin Lymphoma is usually normal.
Abdomen
- Abdominal examination of patients with Non Hodgkin Lymphoma include:
- Abdominal distension
- Abdominal tenderness
- Abdominal mass
- Hepatomegaly
Back
- Back examination of patients with Non Hodgkin Lymphoma is usually normal.
Genitourinary
- Genitourinary examination of patients with Non Hodgkin Lymphoma is usually normal.
Neuromuscular
- Neuromuscular examination of patients with Non Hodgkin Lymphoma is usually normal.
Extremities
- Extremities examination of patients with Non Hodgkin Lymphoma include:
- Peripheral lymphadenopathy
- Joint pain
CNS
Head
-
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/images/8/84/Non_hodgkin%27s_lymphoma05.jpg)
- Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]
-
- Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/index.php/File:Non_hodgkin%27s_lymphoma05.jpg)
Neck
-
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/images/6/6b/Non_hodgkin%27s_lymphoma01.jpg)
- Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]
-
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/images/9/92/Non_hodgkin%27s_lymphoma02.jpg)
- Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]
-
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/images/2/2c/Non_hodgkin%27s_lymphoma03.jpg)
- Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]
-
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/images/6/64/Non_hodgkin%27s_lymphoma04.jpg)
- Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]
-
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/images/4/47/Non_hodgkin%27s_lymphoma07.jpg)
- Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]
-
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/images/4/4c/Non_hodgkin%27s_lymphoma08.jpg)
- Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]
-
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/images/a/aa/Non_hodgkin%27s_lymphoma09.jpg)
- Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]
-
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/images/a/a4/Non_hodgkin%27s_lymphoma10.jpg)
- Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/index.php/File:Non_hodgkin%27s_lymphoma01.jpg)
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/index.php/File:Non_hodgkin%27s_lymphoma02.jpg)
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/index.php/File:Non_hodgkin%27s_lymphoma03.jpg)
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/index.php/File:Non_hodgkin%27s_lymphoma04.jpg)
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/index.php/File:Non_hodgkin%27s_lymphoma07.jpg)
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/index.php/File:Non_hodgkin%27s_lymphoma08.jpg)
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/index.php/File:Non_hodgkin%27s_lymphoma09.jpg)
![:Non hodgkin's lymphoma. Adapted from Dermatology Atlas.[4]](/index.php/File:Non_hodgkin%27s_lymphoma10.jpg)
References
- ↑ Hingorjo MR, Syed S (2008). "Presentation, staging and diagnosis of lymphoma: a clinical perspective". J Ayub Med Coll Abbottabad. 20 (4): 100–3. PMID 19999217.
- ↑ Thacker N, Bakhshi S, Chinnaswamy G, Vora T, Prasad M, Bansal D; et al. (2017). "Management of Non-Hodgkin Lymphoma: ICMR Consensus Document". Indian J Pediatr. 84 (5): 382–392. doi:10.1007/s12098-017-2318-0. PMID 28378140.
- ↑ Armitage JO, Gascoyne RD, Lunning MA, Cavalli F (2017). "Non-Hodgkin lymphoma". Lancet. 390 (10091): 298–310. doi:10.1016/S0140-6736(16)32407-2. PMID 28153383.
- ↑ 4.0 4.1 4.2 4.3 4.4 4.5 4.6 4.7 4.8 4.9 "Dermatology Atlas".