Non-Hodgkin lymphoma other diagnostic studies

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Preeti Singh, M.B.B.S.[2]

Overview

Other diagnostic studies for the diagnosis of non-Hodgkin lymphoma include bone marrow aspiration, bone marrow biopsy, and lumbar puncture.

Other Diagnostic Studies

Lumbar Puncture

Indications

  • Aggressive Non Hodgkin Lymphoma with involvement of bone marrow, epidural, testicular, paranasal sinus, or nasopharyngeal involvement, or two or more extranodal sites[1]
  • High-grade lymphoblastic lymphoma
  • High-grade small noncleaved cell lymphomas (eg, Burkitt and non-Burkitt types)
  • HIV-related lymphoma
  • Primary CNS lymphoma
  • when neurologic signs and symptoms are present

Immunophenotypic Analysis

  • It provides information about lineage and clonality and useful for subclassifying certain lymphoma subtypes which may provide therapeutic and prognostic importance.[1]

Other Studies

  • Bone marrow biopsy
  • Bone marrow aspiration


References

  1. 1.0 1.1 Casulo C, Burack WR, Friedberg JW (2015). "Transformed follicular non-Hodgkin lymphoma". Blood. 125 (1): 40–7. doi:10.1182/blood-2014-04-516815. PMID 25499449.