Multi-drug-resistant tuberculosis risk factors

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]

Overview

Risk factors for multi-drug resistant tuberculosis include exposure to an individual with MDR-TB, previous TB treatment, HIV infection, and a low socioeconomic status.

Risk Factors

• The risk factor for developing multi-drug resistant tuberculosis include:

• Exposure to a patient with MDR-TB
• Previous TB treatment
• HIV infection
• Previous incarceration
• Failed TB treatment
• Relapse following standard TB treatment
• Low income and low socioeconomic class
• Individuals that come from areas of the world where drug-resistant TB is common
• Individuals that have spent time with someone known to have drug-resistant TB disease

• Adverse reactions of the drugs used in the treatment of tuberculosis contribute to the cease of the drug regimen and increases the probability of multi-drug resistance.
• Direct observed treatment plays an important role to avoid drop-outs from tuberculosis medical regimen, which is an important risk factor for developing resistance to the standard medical regimen.

Further information: [[:Tuberculosis risk factors]]