Multi-drug-resistant tuberculosis MRI

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Alejandro Lemor, M.D. [2]

Overwiew

MRI is used for the assessment of extrapulmonary tuberculosis, such as CNS tuberculosis, osteoarticular tuberculosis, Pott's disease, and parotid gland tuberculosis.

MRI

CNS Tuberculosis

  • MRI is most commonly used in cases of CNS infection with tuberculosis.
  • The following findings may be seen in CNS tuberculosis:[1]
  • Ring-enhancing mass in T2 and hypodense lesion in case of a non-caseating tuberculoma.
  • A caseating tuberculoma is seen as a hypodense lesion in both T1 and T2.
  • Cerebral edema
  • Diffuse enhancement in case of meningitis
CNS Tuberculoma
Image courtesy of Dr Praveen Jha, Radiopedia. (original file here) Creative Commons BY-SA-NC
CNS Tuberculoma
Image courtesy of Dr Praveen Jha, Radiopedia. (original file here) Creative Commons BY-SA-NC

Pott's Disease

  • Spinal MRI is the image diagnostic test of choice for spinal tuberculosis.
  • Findings include: [2]
  • Endplate irregularity
  • Irregular anterior aspect of the vertebral bodies
  • Edema and enhancement of the bone marrow.
  • Destruction of vertebral body in severe cases.
Spinal Tuberculosis C6-C7
Image courtesy of Dr Hani Salam, Radiopedia. (original file here) Creative Commons BY-SA-NC
Spinal Tuberculosis C6-C7
Image courtesy of Dr Hani Salam, Radiopedia. (original file here) Creative Commons BY-SA-NC
Spinal Tuberculosis C6-C7
Image courtesy of Dr Hani Salam, Radiopedia. (original file here) Creative Commons BY-SA-NC

Osteoarticular Tuberculosis

  • MRI findings in osteoarticular tuberculosis include:[3]
  • Demineralization
  • Narrowing of the joint space
  • Bone and cartilage erosion
  • Calcifications

Parotid Gland Tuberculosis

  • Tuberculosis infection of the parotid gland con mimic a parotid neoplasm.
  • The MRI shown below reveals a well-defined mass lesion, measuring 16 × 21 × 30 mm in size, hypointense on T1-weighted images, and hyperintense on T2-weighted images with homogenous contrast enhancement, located in the posterior part of the superficial lobe of the right parotid gland.[4]
Image courtesy of Wikimedia Commons.

References

  1. Burrill, Joshua; Williams, Christopher J.; Bain, Gillian; Conder, Gabriel; Hine, Andrew L.; Misra, Rakesh R. (2007). "Tuberculosis: A Radiologic Review1". RadioGraphics. 27 (5): 1255–1273. doi:10.1148/rg.275065176. ISSN 0271-5333.
  2. Torres C, Riascos R, Figueroa R, Gupta RK (2014). "Central nervous system tuberculosis". Top Magn Reson Imaging. 23 (3): 173–89. doi:10.1097/RMR.0000000000000023. PMID 24887691.
  3. Grubisić F, Borić I, Segota A, Kruslin B, Grazio S (2014). "An unusual manifestation of osteoarticular tuberculosis: case report". Acta Clin Croat. 53 (2): 237–41. PMID 25163241.
  4. Birkent, Hakan; Karahatay, Serdar; Akcam, Timur; Durmaz, Abdullah; Ongoru, Onder (2008). "Primary parotid tuberculosis mimicking parotid neoplasm: a case report". Journal of Medical Case Reports. 2 (1): 62. doi:10.1186/1752-1947-2-62. ISSN 1752-1947.

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