Keratin 14
| keratin 14
| |
| Identifiers | |
| Symbol | KRT14 |
| Alt. Symbols | EBS3, EBS4 |
| Entrez | 3861 |
| HUGO | 6416 |
| OMIM | 148066 |
| RefSeq | NM_000526 |
| UniProt | P02533 |
| Other data | |
| Locus | Chr. 17 q12-q21 |
Keratin 14 is a type I cytokeratin. It is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells.
Pathology
Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex.
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Protein: fibrous proteins | |
|---|---|
| Collagen | Type-I (COL1A1) - Type-II (COL2A1) - Type-III - Type-IV - Type-V - Type XI (COL11A2) - Type-XVII - Type-XVIII |
| Keratin/Cytokeratin | type I (10, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21), type II (1, 2A, 3, 4, 5, 6A, 7, 8, 9), Hair (Type I, Type II), Beta |
| other | Elastin - Cytoskeletal |
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