Clitoromegaly
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| Clitoromegaly | |
| ICD-10 | Q52.6 |
| ICD-9 | 752.49 |
| DiseasesDB | 30822 |
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Clitoromegaly (or macroclitoris [1]) is an abnormal enlargement of the clitoris (not to be confused with the normal enlargement of the clitoris seen during sexual arousal).
Although clitoromegaly denotes just a clitoris larger than expected (thus involving some uncertainty about what can be defined as normal), it is commonly seen as a congenital anomaly of the genitalia.
In Atlas of Human Sex Anatomy (1949) by Dr. Robert Latou Dickinson, the normal clitoris is defined as having a crosswise width of 3 to 4 mm. (0.12 - 0.16 inches) and a lengthwise width of 4 to 5 mm (0.16 - 0.20 inches). On the other hand, in Obstetrics and Gynecology medical literature, a frequent definition of clitoromegaly is when there is a CI of greater than 35 mm2 (0.05 inches2), which is almost twice the size given above for an average sized clitoral hood [3].
Presentation
In the most pronounced cases, clitoromegaly is a symptom of intersexuality since the large clitoris resembles a penis (the different grade of genital ambiguity is commonly measured by the Prader classification [2] ranging, in ascending order of masculinisation, from 1: Female external genitalia with clitoromegaly through 5: Pseudo-Phallus looking like normal male external genitalia [4]).
Causes
Clitoromegaly is otherwise a rare condition and can be either present by birth or acquired later in life. If present at birth, congenital adrenal hyperplasia can be one of the causes, since in this condition the adrenal gland of the female fetus produces additional androgens and the newborn baby has ambiguous genitalia which are not clearly male or female.
In acquired clitoromegaly the main cause is due to hormonal imbalance affecting the adult women, as in polycystic ovarian syndrome (PCOS) , arrhenoblastoma and Fraser syndrome).
Clitoromegaly may be acquired through use of anabolic steroids or testosterone supplements, both of which can cause enlargement of the clitoris. This occurs in Female to Male Transsexuals (FtM) after a period of hormone replacement therapy. Like FtM transsexuals, female body-builders who use androgens may also experience enlargement of the clitoris and increases in libido. Women who use testosterone for therapeutic reasons (treating low libido, averting osteoporosis, as part of an anti-depressant regimen, etc) may also experience some enlargement of the clitoris although the dosages warranted for these conditions is much lower.
Deliberately induced clitoris enlargement, as form of female genital body modification, is reported to be achieved through testosterone injections directly in the clitoris shaft.
References
External links
- E. Copcu et al. Idiopathic isolated clitoromegaly: A report of two cases. Reproductive Health 2004, 1:4 doi:10.1186/1742-4755-1-4
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Acknowledgement and Attribution Regarding Sources of Content
Some of the initial content on this page may be incorporated in part from copyleft sources in the public domain including wikis such as Wikipedia and AskDrWiki. Drug information for patients came from the The National Library of Medicine. Infectious disease information may have come from the Centers for Disease Control (CDC). Differential Diagnoses are drawn from clinicians as well as an amalgamation of 3 sources: 1.The Disease Database; 2. Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:3; 3. Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:7 .
