Carcinoid syndrome epidemiology and demographics
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Parminder Dhingra, M.D. [2]
Overview
The incidence of carcinoid syndrome is estimated to be 2 cases per 100,000 individuals worldwide. Carcinoid syndrome is a disease that tends to affect the elderly population. The median age at diagnosis is 60.9 years.Females are more commonly affected with carcinoid syndrome than males. Carcinoid syndrome usually affects individuals of the caucasian race. African American, Latin American, and Asian individuals are less likely to develop carcinoid syndrome.
Epidemiology and Demographics
Prevalence
- Carcinoid tumors represent about 0.5% of all newly diagnosed malignancies.
- Carcinoid tumors account for 75% of all gastrointestinal endocrine tumors.
- Ovarian carcinoid tumors account for 0.3% of all ovarian tumors and 0.5% of carcinoid tumors.[1]
Incidence
- The incidence of carcinoid syndrome is estimated to be 2 cases per 100,000 individuals worldwide.[2]
- Neuroendocrine tumors of the digestive system arising in the tubular gastrointestinal tract and the pancreas are relatively rare.
- The annual incidence in the United States is approximately 3.56 per 100,000 population.[3]
Age
- Carcinoid syndrome is a disease that tends to affect the elderly population.[4]
- Ovarian carcinoid tumors are commonly seen in perimenopausal and postmenopausal women.
- The median age at diagnosis is 60.9 years.[4]
Gender
- Females are more commonly affected with carcinoid syndrome than males.
- Males are more commonly affected with thymic carcinoid tumor than females. The male to female ratio is approximately 3 to 1.[5]
Race
- Carcinoid syndrome usually affects individuals of the Caucasian race.
- African American, Latin American, and Asian individuals are less likely to develop carcinoid syndrome.[4]
References
- ↑ Ovarian carcinoid tumors. Dr Aditya Shetty and Dr Yuranga Weerakkody et al. Radiopaedia 2015. http://radiopaedia.org/articles/ovarian-carcinoid-tumours
- ↑ Epidemiology of carcinoid tumor. National cancer institute. http://www.cancer.gov/types/gi-carcinoid-tumors/hp/gi-carcinoid-treatment-pdq
- ↑ Dasari A, Shen C, Halperin D, Zhao B, Zhou S, Xu Y, Shih T, Yao JC (October 2017). "Trends in the Incidence, Prevalence, and Survival Outcomes in Patients With Neuroendocrine Tumors in the United States". JAMA Oncol. 3 (10): 1335–1342. doi:10.1001/jamaoncol.2017.0589. PMC 5824320. PMID 28448665.
- ↑ 4.0 4.1 4.2 Maggard MA, O'Connell JB, Ko CY (2004). "Updated population-based review of carcinoid tumors". Ann Surg. 240 (1): 117–22. PMC 1356383. PMID 15213627.
- ↑ Thymic carcinoid tumour. Dr Aditya Shetty and Dr Yuranga Weerakkody et al. Radiopaedia 2015. http://radiopaedia.org/articles/thymic-carcinoid-tumour