Bronchioloalveolar carcinoma

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Synonyms and Keywords: Synonym 1; Synonym 2; Synonym 3

Bronchioloalveolar carcinoma
MeSH D002282

WikiDoc Resources for Bronchioloalveolar carcinoma

Articles

Most recent articles on Bronchioloalveolar carcinoma

Most cited articles on Bronchioloalveolar carcinoma

Review articles on Bronchioloalveolar carcinoma

Articles on Bronchioloalveolar carcinoma in N Eng J Med, Lancet, BMJ

Media

Powerpoint slides on Bronchioloalveolar carcinoma

Images of Bronchioloalveolar carcinoma

Photos of Bronchioloalveolar carcinoma

Podcasts & MP3s on Bronchioloalveolar carcinoma

Videos on Bronchioloalveolar carcinoma

Evidence Based Medicine

Cochrane Collaboration on Bronchioloalveolar carcinoma

Bandolier on Bronchioloalveolar carcinoma

TRIP on Bronchioloalveolar carcinoma

Clinical Trials

Ongoing Trials on Bronchioloalveolar carcinoma at Clinical Trials.gov

Trial results on Bronchioloalveolar carcinoma

Clinical Trials on Bronchioloalveolar carcinoma at Google

Guidelines / Policies / Govt

US National Guidelines Clearinghouse on Bronchioloalveolar carcinoma

NICE Guidance on Bronchioloalveolar carcinoma

NHS PRODIGY Guidance

FDA on Bronchioloalveolar carcinoma

CDC on Bronchioloalveolar carcinoma

Books

Books on Bronchioloalveolar carcinoma

News

Bronchioloalveolar carcinoma in the news

Be alerted to news on Bronchioloalveolar carcinoma

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Commentary

Blogs on Bronchioloalveolar carcinoma

Definitions

Definitions of Bronchioloalveolar carcinoma

Patient Resources / Community

Patient resources on Bronchioloalveolar carcinoma

Discussion groups on Bronchioloalveolar carcinoma

Patient Handouts on Bronchioloalveolar carcinoma

Directions to Hospitals Treating Bronchioloalveolar carcinoma

Risk calculators and risk factors for Bronchioloalveolar carcinoma

Healthcare Provider Resources

Symptoms of Bronchioloalveolar carcinoma

Causes & Risk Factors for Bronchioloalveolar carcinoma

Diagnostic studies for Bronchioloalveolar carcinoma

Treatment of Bronchioloalveolar carcinoma

Continuing Medical Education (CME)

CME Programs on Bronchioloalveolar carcinoma

International

Bronchioloalveolar carcinoma en Espanol

Bronchioloalveolar carcinoma en Francais

Business

Bronchioloalveolar carcinoma in the Marketplace

Patents on Bronchioloalveolar carcinoma

Experimental / Informatics

List of terms related to Bronchioloalveolar carcinoma

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Manpreet Kaur, MD [2]

Overview

Bronchioloalveolar carcinoma (BAC) is a rare type of lung cancer. It occurs more frequently among never-smokers, women and Asians.[1]

By definition, BAC is not an invasive tumor. Therefore, pathologists classify it as a form of carcinoma in situ (CIS). However, unlike other forms of CIS, its behavior is malignant, often lethal. Major surgery, either a lobectomy or a pneumonectomy, is needed to control it, and recurrences are frequent. For this reason, oncologists classify it among the other malignant tumors, which are invasive tumors.

Historical prespective

  • Bronchioloalveolar carcinoma was first discovered by Dr. Averill Liebow, in the year of 1960.
  • In 1999, the World Health Organization has given the term 'Pure BAC' as a subtype of adenocarcinoma that doesn’t Invase.
  • In [year], [gene] mutations were first identified in the pathogenesis of [disease name].
  • In [year], the first [discovery] was developed by [scientist] to treat/diagnose [disease name].

Classification

Bronchioloalveolar carcinoma is a sub-type of lung adenocarcinoma. However it is distinct from other lung adenocarcinomas by different clinical features, prognosis and response to treatment.[2]

Pathophysiology

Microscopic Pathology

Causes

  • [Disease name] may be caused by either [cause1], [cause2], or [cause3].
  • [Disease name] is caused by a mutation in the [gene1], [gene2], or [gene3] gene[s].
  • There are no established causes for [disease name].

Differentiating [disease name] from other Diseases

  • [Disease name] must be differentiated from other diseases that cause [clinical feature 1], [clinical feature 2], and [clinical feature 3], such as:
  • [Differential dx1]
  • [Differential dx2]
  • [Differential dx3]

Epidemiology and Demographics

  • The prevalence of [disease name] is approximately [number or range] per 100,000 individuals worldwide.
  • In [year], the incidence of [disease name] was estimated to be [number or range] cases per 100,000 individuals in [location].

Age

  • Patients of all age groups may develop [disease name].
  • [Disease name] is more commonly observed among patients aged [age range] years old.
  • [Disease name] is more commonly observed among [elderly patients/young patients/children].

Gender

  • [Disease name] affects men and women equally.
  • [Gender 1] are more commonly affected with [disease name] than [gender 2].
  • The [gender 1] to [Gender 2] ratio is approximately [number > 1] to 1.

Race

  • There is no racial predilection for [disease name].
  • [Disease name] usually affects individuals of the [race 1] race.
  • [Race 2] individuals are less likely to develop [disease name].

Risk Factors

  • Common risk factors in the development of [disease name] are [risk factor 1], [risk factor 2], [risk factor 3], and [risk factor 4].

Natural History, Complications and Prognosis

  • The majority of patients with [disease name] remain asymptomatic for [duration/years].
  • Early clinical features include [manifestation 1], [manifestation 2], and [manifestation 3].
  • If left untreated, [#%] of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].
  • Common complications of [disease name] include [complication 1], [complication 2], and [complication 3].
  • Prognosis is generally [excellent/good/poor], and the [1/5/10­year mortality/survival rate] of patients with [disease name] is approximately [#%].

Diagnosis

Diagnostic Criteria

  • The diagnosis of [disease name] is made when at least [number] of the following [number] diagnostic criteria are met:
  • [criterion 1]
  • [criterion 2]
  • [criterion 3]
  • [criterion 4]

Symptoms

  • [Disease name] is usually asymptomatic.
  • Symptoms of [disease name] may include the following:
  • [symptom 1]
  • [symptom 2]
  • [symptom 3]
  • [symptom 4]
  • [symptom 5]
  • [symptom 6]

Physical Examination

  • Patients with [disease name] usually appear [general appearance].
  • Physical examination may be remarkable for:
  • [finding 1]
  • [finding 2]
  • [finding 3]
  • [finding 4]
  • [finding 5]
  • [finding 6]

Laboratory Findings

  • There are no specific laboratory findings associated with [disease name].
  • A [positive/negative] [test name] is diagnostic of [disease name].
  • An [elevated/reduced] concentration of [serum/blood/urinary/CSF/other] [lab test] is diagnostic of [disease name].
  • Other laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].

Imaging Findings

  • There are no [imaging study] findings associated with [disease name].
  • [Imaging study 1] is the imaging modality of choice for [disease name].
  • On [imaging study 1], [disease name] is characterized by [finding 1], [finding 2], and [finding 3].
  • [Imaging study 2] may demonstrate [finding 1], [finding 2], and [finding 3].

Other Diagnostic Studies

  • [Disease name] may also be diagnosed using [diagnostic study name].
  • Findings on [diagnostic study name] include [finding 1], [finding 2], and [finding 3].

Treatment

Medical Therapy

  • There is no treatment for [disease name]; the mainstay of therapy is supportive care.
  • The mainstay of therapy for [disease name] is [medical therapy 1] and [medical therapy 2].
  • [Medical therapy 1] acts by [mechanism of action 1].
  • Response to [medical therapy 1] can be monitored with [test/physical finding/imaging] every [frequency/duration].

Surgery

  • Surgery is the mainstay of therapy for [disease name].
  • [Surgical procedure] in conjunction with [chemotherapy/radiation] is the most common approach to the treatment of [disease name].
  • [Surgical procedure] can only be performed for patients with [disease stage] [disease name].

Prevention

  • There are no primary preventive measures available for [disease name].
  • Once diagnosed and successfully treated, patients with [disease name] are followed-up every [duration]. Follow-up testing includes [test 1], [test 2], and [test 3]. Effective measures for the primary prevention of [disease name] include [measure1], [measure2], and [measure3].

References

  1. Raz, DJ (Mar 2006). "Bronchioloalveolar carcinoma: a review". Clinical Lung Cancer. Cancer Information Group. 7 (5): 313–322. 
  2. Lee, KS (Nov–Dec 1997). "Bronchioloalveolar carcinoma: clinical, histopathologic, and radiologic findings" (PDF). RadioGraphics. 17 (6): 1345–1357. PMID 9397450. Retrieved 2007-12-03. 

de:Bronchioloalveoläres Karzinom



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