Adenocarcinoma
| Adenocarcinoma, NOS | |
| Adenocarcinoma of the stomach.The photo above is asen face view of the ulcer. The pyloric margin is to the left. The ulcer is on the lesser curvature. (Courtesy of Ed Uthman, MD) | |
| ICD-9 | 151.0, 182.0 |
| ICD-O: | M8140/3 |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Adenocarcinoma is a form of carcinoma that originates in glandular tissue. To be classified as adenocarcinoma, the cells do not necessarily need to be part of a gland, as long as they have secretory properties. This form of carcinoma can occur in some higher mammals, including humans.[1]
The term adenocarcinoma is derived from 'adeno' meaning 'pertaining to a gland' and 'carcinoma', which describes a cancer that has developed in the epithelial cells.
It can first present as an adenoma (a glandular tumor that is benign).
Pathophysiology
Examples of tissues where adenocarcinomas may arise:
- Breast cancer
- Colon cancer
- Lung cancer
- Prostate cancer
- Stomach cancer
- Pancreatic cancer (99% of pancreatic cancers are ductal adenocarcinomas [2])
- Cervical cancer
- Vaginal cancer
Gross Pathology
This cancer presented in a 40-year-old woman complaining of abdominal pain. Endoscopically it was a "very suspicious" ulcer. Biopsy showed diffusely infiltrating signet ring cell adenocarcinoma. These are gross photos of the subtotal gastrectomy specimen. The photo above is a seen face view of the ulcer. The pyloric margin is to the left. The ulcer is on the lesser curvature.
References
- ↑ Fauquier, D.A., Gulland, F.M.D.,(Marine Mammal Center), Haulena, M., Spraker, T., ‘’Biliary adenocarcinoma in a stranded Northern elephant seal (‘’Mirounga angustirortsis’‘)’‘, Journal of Wildlife Diseases 39(3):723-726 (2003)
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