Acute lymphoblastic leukemia echocardiography and ultrasound

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Acute lymphoblastic leukemia Microchapters


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Case #1

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Shyam Patel [2]


Additional imaging studies that can be useful in acute lymphoblastic leukemia include echocardiogram and ultrasound. Echocardiogram is useful for assessing cardiac function in patients receiving anthracycline chemotherapy. Ultrasound is useful for assessing for deep vein thrombosis which is a common complication of acute lymphoblastic leukemia. Ultrasound can also assess for spleen size.

Echocardiograph and ultrasound



Splenomegaly ultrasonography-Case courtesy of Dr Ian Bickle, via[6]

Images of the left femur with florid periosteal reaction and paraosteal soft tissue, giving layers rather like an onion.Two enlarged lymph nodes on the medial aspect of the kneecourtesy of Dr Ian Bickle,, rID: 40019


  1. Neilan TG, Coelho-Filho OR, Pena-Herrera D, Shah RV, Jerosch-Herold M, Francis SA; et al. (2012). "Left ventricular mass in patients with a cardiomyopathy after treatment with anthracyclines". Am J Cardiol. 110 (11): 1679–86. doi:10.1016/j.amjcard.2012.07.040. PMC 3496816. PMID 22917553.
  2. Mina A, Rafei H, Khalil M, Hassoun Y, Nasser Z, Tfayli A (2015). "Role of baseline echocardiography prior to initiation of anthracycline-based chemotherapy in breast cancer patients". BMC Cancer. 15: 10. doi:10.1186/s12885-014-1004-0. PMC 4311428. PMID 25605569.
  3. McGowan JV, Chung R, Maulik A, Piotrowska I, Walker JM, Yellon DM (2017). "Anthracycline Chemotherapy and Cardiotoxicity". Cardiovasc Drugs Ther. 31 (1): 63–75. doi:10.1007/s10557-016-6711-0. PMC 5346598. PMID 28185035.
  4. Zitek T, Baydoun J, Yepez S, Forred W, Slattery DE (2016). "Mistakes and Pitfalls Associated with Two-Point Compression Ultrasound for Deep Vein Thrombosis". West J Emerg Med. 17 (2): 201–8. doi:10.5811/westjem.2016.1.29335. PMC 4786247. PMID 26973753.
  5. Saboo SS, Krajewski KM, O'Regan KN, Giardino A, Brown JR, Ramaiya N; et al. (2012). "Spleen in haematological malignancies: spectrum of imaging findings". Br J Radiol. 85 (1009): 81–92. doi:10.1259/bjr/31542964. PMC 3473934. PMID 22096219.
  6. From the case <"">rID: 52825