Acquired hemolytic anemia

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Acquired hemolytic anemia
ICD-10 D59.
ICD-9 283

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]


Acquired hemolytic anemia can be divided into immune and non-immune mediated forms of hemolytic anemia.

Immune

Immune mediated hemolytic anemia (direct Coombs test is positive)

Non-immune

Non-immune mediated hemolytic anemia (direct Coombs test is negative)

Drug induced hemolysis

Drug induced hemolysis has large clinical relevance. It occurs when drugs actively provoke red blood cell destruction. It can be divided in the following manner:

A total of four mechanisms are usually described, but there is some evidence that these mechanisms may overlap.[1]

References

  1. Wright MS (1999). "Drug-induced hemolytic anemias: increasing complications to therapeutic interventions". Clin Lab Sci. 12 (2): 115–8. PMID 10387489. 

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